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Topictal (Topiramate)

Topictal is a prescription drug. It comes in four forms: immediate-release tablets, immediate-release sprinkle capsules, extended-release capsules, and extended-release sprinkle capsules. All forms are taken by mouth. Topictal oral tablet is available as the brand-name drug Topictal. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in every strength or form as the brand-name drug. This drug may be taken in combination with other drugs to treat epilepsy.

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Topictal is used alone or with other medications to treat certain types of seizures including primary generalized tonic-clonic seizures (formerly known as a grand mal seizure; seizure that involves the entire body) and partial onset seizures (seizures that involve only one part of the brain). Topictal is also used with other medications to control seizures in people who have Lennox-Gastaut syndrome (a disorder that causes seizures and developmental delays). Topictal is also used to prevent migraine headaches but not to relieve the pain of migraine headaches when they occur. Topictal is in a class of medications called anticonvulsants. It works by decreasing abnormal excitement in the brain.

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Effect of temperature and antioxidants upon the lipoxidase-catalyzed oxidation of sodium linoleate. Sex hormone dependency of diethylnitrosamine-induced liver tumors in mice and chemoprevention by leuprorelin.

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In this study, three different lung cancer cell lines and three different primary cell cultures established from patients with lung cancer (two patients with squamous cell lung carcinoma and one with adenocarcinoma) were screened for sensitivity to adenoviral delivery of TRAIL. The role of Notch in vascular development and arterial differentiation is well known.

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Each year more than 150,000 people in Australia and New Zealand experience burning of sufficient severity for them to seek medical help, with 400 people dying annually. Nine MAbs were specific to the external gp125 and three reacted with the transmembrane gp36. Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats. Cholinergic and adrenergic mechanisms of increase in gastric secretion in response to acute hypercalcemia in duodenal ulcer

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Optimized Prediction of Extreme Treatment Outcomes in Ovarian Cancer. Here the expanding FRW universe emerges be-hind a subluminous blast wave that explodes outward from the FRW center at the instant of the big bang. All consecutive donors in these centres filled out an anonymous questionnaire when they started their hormonal stimulation, asking for their socio-demographic and fertility-related characteristics, their motivations and compensation. Within 5 months of the onset of symptoms, the entire medial tibial plateau collapsed down into the metaphyseal region, causing severe varus deformity, instability, and inability to walk without crutches and a hinged knee brace. This observed increase in use is not confined to high-volume hospitals.

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A review of the clinical efficacy of the Oral-B oscillating/rotating power toothbrush and the Philips Sonicare toothbrush in normal subject populations. To raise awareness among healthcare providers about the clinical and laboratory findings in acute and chronic food protein-induced enterocolitis syndrome (FPIES). After 18 h of in vitro culture, it co-localizes with beta-tubulin at the spindle apparatus. Using a consensus-based approach, they assessed 14 commonly used DED severity criteria.

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Brk bound to a Dpp response element of the Ultrabithorax (Ubx) midgut enhancer at a sequence that overlaps a binding site for the Smad protein, Mothers Against Dpp (Mad). Influence of pH on pesticide sorption by soil containing wheat residue-derived char.

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The identification of 1,3-oxazolidine-2-thiones and 1,3-thiazolidine-2-thiones from the reaction of glucose with benzyl isothiocyanate. Here, we review in vivo studies in genetically altered mice that support the notion that monocyte chemoattractant protein-1 (a member of the chemokine family of chemotactic cytokines) and chemokine receptor 2 (its cognate receptor) play important roles in this recruitment. To evaluate the methodology and efficacy of transcatheter closure of postoperative residual VSD in children. The dopamine antagonists are used in the treatment dysmotility-like dyspepsia and could relieve the dyspeptic symptoms. Visual acuity (VA) ranged between 20/63 and 20/32 (median 20/32) at first presentation and between 20/2000 (counting fingers) and 20/20 (median 20/400) at last presentation.

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No difference in migration pattern was observed after treatment of the nuclear extract with DNase I or RNase. HCV has been postulated to have a relationship with B cell lymphomas.

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Macrophage activation syndrome and reactive hemophagocytic lymphohistiocytosis: the same entities? Cardiac index was insensitive, usually remaining normal until ejection fraction was less than 0.40.

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Intracellular domain of desmoglein 3 (pemphigus vulgaris antigen) confers adhesive function on the extracellular domain of E-cadherin without binding catenins. Also, the risk of gastrointestinal haemorrhage with any NSAIDs must always be remembered. Nhp6 bound to nucleosomes and made at least two changes in them: the nucleosomal DNA became more sensitive to DNase I at specific sites, and the nucleosomes became competent to bind Spt16-Pob3 to form yFACT.nucleosome complexes.

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Comparison of the crystal structure of the PSBD bound to E3 with the solution structure of uncomplexed PSBD described here indicates that the PSBD undergoes almost no conformational change upon binding to E3. Revisiting the role of retinoid signaling in skeletal development.

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The incorporation and oxidation of 14C-Methionine were compared between fresh recovered and cultured embryos at the 1-cell to 16-cell stages. Multi-slice computed tomography of myocardial bridge and mural coronary artery and clinical significance thereof

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Results of the post-market Registry to Evaluate the HeartWare Left Ventricular Assist System (ReVOLVE). As these effects are frequently non-specific and affect many cell types, some toxicities may be detected and monitored by HCA of peripheral blood cells, such as for anticancer and anti-infective drugs. Antibiotic OM-173 components alpha A, alpha E, alpha B, beta A and beta E were isolated from the fermentation broth of strain OM-173 by solvent extraction, silica gel chromatography and preparative thin-layer chromatography. Normal cardiac rhythm during hypocaloric diets of varying carbohydrate content.

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Adrenalectomy altered the response of BNST neurons to medial amygdala (AME) stimulation, increasing the proportion of excitatory responses and reducing the number of cells inhibited. Valve replacement in an infant with congenital mitral stenosis--report of a case which showed hemodynamics similar to that of hypoplastic left heart syndrome in neonatal period To our knowledge, there have been no previous reports of management of feline carpal hyperextension injuries in this fashion. Our numerical results show that fractional order can affect not only the stability of the system without harvesting terms, but also the switching times from stability to instability and to stability. The effect of flutamide on the physical working capacity and activity of some of the key enzymes for the energy supply in adult rats.

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Impact of similar severity did not produce ventricular injury (p less than 0.01) in either 11 control or 10 animals injected with isoproterenol and experiencing transient hypotension. Application of D-amphetamine and fluoxetine revealed well-defined functional structure underlying the widespread signal changes detected via standard methods. Using an experimental arthritis model in IL-6(-/-) mice, we have established a critical role for the soluble IL-6R in joint inflammation. Role of quorum sensing in resistance of Serratia plymuthica against Acanthamoeba castellanii. This article describes the complex nursing and social needs of a patient and her carer which were addressed before discharge home from units for the care of older people.

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Determination of aflatoxin B1 in agricultural commodities by time-resolved fluoroimmunoassay and immunoenzymometric assay. We will review islet transplantation, as well as the mechanisms underlying insulin transcription, translation and glucose stimulated insulin release. Groups were compared on demographics, psychiatric history, psychopathology, medication side effects, and social functioning. These findings identify NF-kappaB as one of the major mediators of Notch1-induced transformation and suggest that the NF-kappaB pathway is a potential target of future therapies of T-ALL. Molecular analysis of the HLA-DRB genes in two tribes of Brazilian Indians.

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Sonographic measurement of the size of the lesions from these 11 patients ranged from 2 cm to 3.7 cm (average 2.77 cm). In an observational study of 1-year weight changes following the initiation of SUs, metformin, insulin or TZDs, we found similar but somewhat smaller weight changes than those previously reported in clinical trials.

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She was treated with oral contraceptive pills and the symptoms were resolved. Four weeks after the last G-CSF injection vascular lumina were free of blood, but vascular epithelium layer was thick. Oxalate modulates thiobarbituric acid reactive species (TBARS) production in supernatants of homogenates from rat brain, liver and kidney: effect of diphenyl diselenide and diphenyl ditelluride.

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In subjects with tetraplegia on paraplegia, respectively, strong correlation coefficients were found for measurements of total lung capacity (.86 and .97), functional residual capacity (.87 and .96), and residual volume (.77 and .85). The transforming capacity of EphA2 is related to the failure of EphA2 to interact with its cell-attached ligands.

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Although phosphomannose isomerase, in contrast to phosphoglucose isomerase, is stereospecific for beta-D-mannose-6-phosphate, the alpha anomer of D-mannose (2 mg/ml) was significantly more effective than equilibrated D-mannose in stimulating insulin release. It is observed that the inelastic interactions depend not only on the electron energy and the current intensity but also on the electron emission regime of the STM tip.

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All patients underwent transthoracic echocardiography to obtain systolic myocardial velocity (Sm), longitudinal SS, and SSR from basal, mid, and apical segments of anterior and inferior walls in two-chamber apical view. Cesarean hysterectomy was performed on 15 pregnant baboons of known gestational age in the last third of pregnancy, five of them during spontaneous term labor. To investigate the effect of different assist levels during proportional assist ventilation (PAV) on patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). The growing oocyte forms pseudopodia and cytoplasmic processes which move apart the epithelial-muscle cells, reach the mesogloea and come in contact with the gastroderm cells.

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Gene recombination was used to get chimeric F proteins NDV-C1 and hPIV-C1 by exchanging NDV F-1 and hPIV F-1 each other, and NDV-C2 and hPIV-C2 were also obtained by the same way. This suggest that some essential hypertensives, with suppressed renin activity, may have an impairment in the cortisol inactivation catalyzed by the enzyme 11betaHSD2, whose low activity in LREH patients could be associated with the length of CA-repeat microsatellite in intron 1 of the HSD11B2 gene.

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Twenty-one patients who underwent reconstruction of the cervical oesophagus with an ileal autograft were studied, with a follow-up period of one to .58 months. These increases lasted 2 to 3 hours longer with bupivacaine than lidocaine.

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The effect of light transmission, as influenced by restorative material type, shade, and thickness on resin cement cure was also determined. Renal function in miners intermittently exposed to elemental mercury vapour. New approaches to therapy of Helicobacterpylori infection (by the materials of the Maastricht Consensus-IV, Florence, 2010) Transforming growth factor-beta1 appears to play important roles in normal wound healing by increasing synthesis of extracellular matrix components. We subcutaneously injected J558 myeloma cells in BALB/c mice and supplemented OPP orally at 1,500 ppm gallic acid equivalent.

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Survey of prescriptions for peptic ulcer drugs (ACT class AOB2) in Iceland. Content of osteocyte in bone tissue is the most abundant, the most widely distributed, and embedding the cells in the mineralized bone matrix, the life can be close to the life of the body.

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When these optimal methods are used, these three commercial workstations do not differ significantly in acquisition of accurate polyp measurements at routine dose settings. Pregnant Wistar rats were daily injected with 5 mg sulpiride into the peritoneal cavity starting on day 14 of gestation.

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Frequency of Natural Resistance within NS5a Replication Complex Domain in Hepatitis C Genotypes 1a, 1b: Possible Implication of Subtype-Specific Resistance Selection in Multiple Direct Acting Antivirals Drugs Combination Treatment. Accordingly, combinations of biomarkers probably will be needed to provide a more complete characterization of the spectrum of pharmacologic response.

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Addressing the ethical problems of randomized and placebo-controlled trials of CPAP. Within each sentence type condition, half of the sentences contained a syntactic violation. Etomidate concentrations in brain tissue were obtained by high-performance liquid chromatography. Antimicrobial susceptibility patterns of bacterial isolates at the American University Medical Center in Lebanon. None of the mutants in the C-terminal domain of LPL showed a loss of activity or a reduction in heparin binding affinity.

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Thus, early initiation of a comprehensive geriatric health examination and a multidomain intervention such as diet, exercise, cognitive training, and vascular risk monitoring may be useful to prevent frailty and sarcopenia in community-dwelling older adults. Impaired ROS Scavenging System in Human Induced Pluripotent Stem Cells Generated from Patients with MERRF Syndrome.

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To describe strategies for enhancing information, motivation, and skills related to changes in diabetes self-management behavior among community-dwelling older adults in Korea. This article provides a review of current understanding of the epidemiology of cardiovascular disease, particularly, coronary heart disease (CHD), stroke and related risk factors in Asian Indian population.

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Healthy male volunteers aged 18-40 years (12 in the single-dose study, 24 in the repeated-dose study). Current food chain information provides insufficient information for modern meat inspection of pigs.

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This entity should be included in the differential diagnosis of lower GI mucosal injury in a setting of uremia and hyperkalemia. An alternative is to reconstruct a 3D patient-specific volume data from 2D X-ray images.

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Logistic regression was used to identify the predicting factors of failure of enalapril ratiopharm 10 mg tabletten tavor needle aspiration. Compensation of the role of vitamin D in the skeletal system by calcium High-performance liquid chromatography (HPLC) was used to study the protein content of aqueous humour in 17 cataract patients. S100A9 and EGFR gene signatures predict disease progression in muscle invasive bladder cancer patients after chemotherapy.

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Under limited angle conditions, CBCT is reduced to FDTS, where only a subset of projection data are used for reconstruction. plaunazide 20 mg 12 5mg Therefore, we assessed the prognostic values of CRP in ischemic stroke. Transient pharmacological inhibition of STAT3 partially prevents muscle wasting.

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We describe a new anterolateral retroperitoneal approach, which is safe and reproducible to access the disc spaces from L1 to S1 inclusive, obviating the need for a separate direct anterior approach to access L5/S1. Cadmium acyclovir for herpes zoster dose encephalopathy: a report with elemental analysis and pathological findings. The overall results suggest that the photoperoxidation was probably initiated by organic radicals obtained from the irradiation of KPF and NAP and the inhibition by copper could be attributed to its interaction with the peroxyl radicals of the drug and/or the liposomes, breaking the propagation of the radical chain. On the other hand, the TGF-beta1-mediated expansion of the mesangial ECM is dominated by the normal components.

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Research on hypertension in Mexico is principally oriented toward development of clinical trials that study specific aspects of the condition in an isolated manner and without a perspective that places the health problem in context and without approaching its main components. Conbercept pretreatment could be an effective adjunct to vitrectomy in accelerating postoperative vitreous clear-up and acquiring stable visual acuity restoration for PDR. The capillary permeability surface product was found to be significantly increased in central nervous system lymphomas compared with glioblastoma multiforme, medulloblastomas, and metastases. The purpose of our study was to analyze changes in the ventral horn produced by gliopathy determined by the suffering of motor neurons following spared nerve injury (SNI) of the sciatic nerve and how the intrathecal (i.t.) administration of GM6001 (a MMPs inhibitor) or the NGF mimetic peptide BB14 modulate these events. However, a teva-rabeprazole vs nexium recent analysis of the genome of the soil bacterium Azotobacter vinelandii DJ revealed an abundance of highly similar homologs among carbohydrate metabolism genes.

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Determination of Norfloxacin by square-wave adsorptive voltammetry on a glassy carbon electrode. LSC detection of platelets reliably reproduced well-described findings of thrombin-induced platelet-endothelial cell adhesion. diclo dispers 50 mg beipackzettel The usefulness of IPH and DPH in occult blood detection has been examined and compared with benzidine and stanoccult methods.

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Since dopamine receptors are the primary targets in the treatment of schizophrenia, improved therapy may be obtained by drugs that selectively target a particular subtype of silvergate pharmaceuticals enalapril dopamine receptor. Early after infection there was a depression in CFUE number in bone marrow and spleen, followed by an increase of the CFUE concentration, earlier and more pronounced in the spleen than in the marrow. Bioinformatics and statistical methods were used to analyze the microbial community structure and diversity. Modulating biochemical perturbations during 72-hour machine perfusion of kidneys: role of preservation solution.

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Complex segregation analysis composicion atomoxetine dosage of tongue pigmentation in 493 nuclear families fails to indicate significant evidence for incomplete recessivity, polygenic variation, or an effect of sibship environment, thus establishing simple Mendelian inheritance for the trait. Since it is the E3 ubiquitin ligase that recognizes the target protein and provides the specificity and selectivity for ubiquitination, this review highlights known examples of E3 ligases in the testis and the differing roles that they play in maintaining functional spermatogenesis. Here we report the successful establishment of ES-like cells from neonatal mouse testis. The implants were surrounded by gaps of 2 mm, and the follow-up period was 12 weeks. Efficacy of new devices for behavior modification therapy for obesity

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Phytoadaptogen correction of clinical and immunobiological parameters in patients with benign prostatic hyperplasia. A young girl presented with Budd-Chiari gel flexen syndrome (BCS) with narrowing of the retrohepatic segment of inferior vena cava (VC).