The purpose of this study was to elucidate the mechanism of action of Secam on concanavalin A (Con A)-induced murine T-cell proliferation. Possible neuroleptic malignant syndrome related to concomitant treatment with paroxetine and Secam. This study in healthy recreational CNS depressant users showed that single doses of brivaracetam 50mg (therapeutic single dose) had lower sedative, positive, and negative drug effects than Secam, while brivaracetam 200 and 1000mg (supratherapeutic single doses) were more similar to Secam.
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