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We conducted a systematic review of published clinical trials of single agent versus combined chemotherapy as salvage treatment in previously treated UC patients. The determination of 11 REEs in carpet-forming moss species (Hypnum cupressiforme) collected from 44 sampling sites over the whole territory of the country were done by using epithermal neutron activation analysis (ENAA) at IBR-2 fast pulsed reactor in Dubna.

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As experience with zafirlukast accumulates, it is expected that the drug will be positioned more definitively in national and international treatment guidelines. One of the factors promoting oxidative/halogenating modification of low-density lipoproteins (LDL) is myeloperoxidase (MPO).

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The recombinant MPO1 protein utilized N-methylputrescine more efficiently than other diamines. Hypothalamic involvement in the pituitary-adrenocortical response to stress stimuli. To test this hypothesis we studied aggregation of mouse fibroblast L cell clones that expressed chimeric cDNAs encoding the EC domain of E-cadherin with various IC domains. To construct a questionnaire for detection of sleep disorders and determine its reliability and validity.

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PPD and hsp65 induced monoarthritis initiates spontaneous recurrent flares in Lewis rats. Proposals for optimization of the international phage typing system for Listeria monocytogenes: combined analysis of phage lytic spectrum and variability of typing results. Randomized controlled trials (RCTs) and cohort and preclinical studies identified in electronic databases were reviewed.

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Case reports were collected from women developing migraine aura related to use of estrogen replacement therapy. Macropinocytosis (fluid uptake) and phagocytosis (particle uptake) are processes that result in the formation of intracellular membrane enclosed vacuoles termed macropinosomes and phagosomes, respectively. We demonstrate that signaling through ERK, but not p38 or JNK, is required for the spontaneous neurite initiation and extension.

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The continuously growing mouse incisors are an excellent model for studying the molecular mechanisms of cell homeostasis, renewal, and repair. Patients undergoing radical surgical treatment of head and neck neoplasms often are seen with a history of cirrhotic liver disease, electrolyte abnormalities, and other stigma of chronic disease. The energy and oscillator strength of electronic transitions of chlorophyll (Chl)-amino acid complexes were calculated by using molecular orbital methods.

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Observation of megakaryocytic features of the bone marrow in 300 cases of acute leukemia We analyzed data from the Vaccine Adverse Event Reporting System (VAERS) reported from July 1, 1990 through March 31, 1992. These models are less relevant to lower vertebrates such as fish or amphibians where exposure of embryos is direct.

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The results indicated significant main effects for set size and decision type and an interaction between treatment and session. Electron microscopic and morphometric studies of the main kidney segment of male and female rats following castration and testosterone substitution A consistent rise in plasma prolactin was also evident after the injection of 1 microgram of either arginine vasopressin, lysine vasopressin or AVT.

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Arginine vasopressin modulates the central action of angiotensin II in the dog. Despite therapeutic advances, non-Hodgkin lymphomas (NHL) remain incurable. Pancreatic resection had better results than multiple enucleations.

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Indeed, miR-124a overexpression led to decreased FoxA2 expression and IAPP promoter occupancy and to a significant reduction in IAPP mRNA and protein expression and also effectively inhibited TXNIP-induced IAPP expression. An exception to this rule is leiomyosarcoma, a rare form of primary cardiac sarcoma that occurs predominantly in the left atrium, as does cardiac myxoma. These data suggest that bilateral priming can enhance the efficacy of Wii-based Movement Therapy, particularly for patients with low motor function after a stroke. A 50-year-old man with hepatic cirrhosis and acute infective endocarditis underwent aortic valve replacement.

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The willingness of US pediatric dentists to use atraumatic restorative treatment (ART) with their patients: a conjoint analysis. Furthermore changes in mean platelet volume appear to play a more important role in haemostasis than changes in platelet count. There is not enough evidence to evaluate the routine use of mucolytics for bronchiectasis. The patient was in stage II, and myeloma protein was detectable.

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Hospital performance within a given hospital varies by patient subgroup. To determine the spontaneous resolving rate of congenital nasolacrimal duct obstruction (CNDO) and the success rate of late probing after age 18 months. The digitization and comprehensive classification of odors were accomplished by using artificial odor maps constructed through this system.

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Data for these questions may derive from animal experiments, human metabolic studies, observational epidemiologic investigations (including ecologic studies), and randomized trials. Both duplex ultrasonography and computed tomography revealed thrombosis of the distal inferior vena cava (IVC) and both iliac and femoral veins. Lactation induced a significant increase of resistin expression in adipose tIssue compared with that in the dry period, and decreased resistin expression in the mammary gland. It is considered that the in vivo erythrocyte sensitization induced by SgE injection initiates the erythrocytic changes observed and that the underlying mechanism responsible for the subsequent development of the haemolytic anaemia is immunologically mediated. A segmental control strategy appears to exist during lifting that works from the upper to lower torso based on peak electromyographic activity activity.

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Western blot analysis using antibodies to mature NGF-beta and to proNGF domain demonstrated a significant decrease in mature NGF-beta at gestational d 14 and 21 (term pregnancy) and 1 d postpartum, which paralleled a remarkable accumulation of the 26-28-, 32-, and 60-kDa proNGF forms. The animals were sacrificed at 0 hr., 15, 30 and 60 days after extraction, and the samples were processed. Spondylocostal dysostosis and urinary tract anomaly: definition and review of an entity. Pathophysiological hypothesis regarding the role of nicotinamide in the genesis of niacin-induced macular edema Plasma and peripheral blood mononuclear cells were collected from each individual for the series of immunological tests listed in the following results section.

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(three Bacteroides asaccharolyticus and one strain each of Bacteroides oralis, Bacteroides intermedius, Bacteroides biacutus, Bacteroides vulgatus, and Bacteroides ruminicola subsp. The objective of this study was to determine the prevalence of food insecurity within an urban population of social disadvantage in readiness for a local health promotion response.

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Out-of-hospital cardiac arrest is a frequent cause of death in Europe. Thus, uptake of blood-borne NGF could affect the hypothalamic-pituitary-adrenal axis via binding to NGF receptors present in the hippocampus.

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All the patients underwent examination of the immune-inflammatory status--the cytokines: interleukin (IL) 6, IL-8, IL-12, tumor necrosis factor-alpha (TNF-alpha), transforming growth factor-beta1, endotoxin, cellular immune parameters, and cardiac structure and function by echocardiography. The five senses of sight, hearing, smell, taste, and touch, enumerated by Aristotle, were incremented in the early-nineteenth century by the muscle sense, multiple dimensions of touch, and a movement sense. Gastric intramucosal measurements as an indicator of splanchnic hypoperfusion and blood samples were obtained at admission to the medical intensive care unit and repeated during 48 hrs.

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The pattern of wnt-1 expression in the hindwing discs was similar to that in the butterfly Precis coenia but subtle differences existed in forewing discs of the two species, which correlated well with the absence of proximal bands of pigmentation in the adult Bombyx wings. Neonatal nutrition, adult antioxidant defences and sexual attractiveness in the zebra finch.

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Unencapsulated Haemophilus influenzae frequently causes noninvasive upper respiratory tract infections in children but can also cause invasive disease, especially in older adults. He responded to oral and topical steroids and an increase in cyclosporine dose. Specific formation of arachidonic acid and eicosapentaenoic acid by a front-end Delta5-desaturase from Phytophthora megasperma. A 69-year-old man with long-standing silicone oil tamponade and an epiretinal membrane at the posterior pole in his right eye (RE) underwent silicone oil/BSS exchange with epiretinal membrane peeling. We believe that ultrasound is safe enough to use in any pregnant woman at any gestational age as often as the clinical indications are present, without need for informed consent (Hohler, 1982).

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However, there is extreme variation overall in the findings of available trials, and-until this variation is accounted for-it is premature to recommend rHuEPO as standard treatment for the anemia of prematurity. Electrical storm in implantable cardioverter-defibrillator (ICD) recipients is a dramatic experience for the patient and a hard emergency for the cardiology team. Conjunctivitis persisted for at least 18 days after chlamydiae no longer were detectable in conjunctival smears. GABA(A) receptor blockade in the dlSC evoked a vigorous escape behavior, expressed by rapid running, jumps and turns, as compared to control.

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In the present study, we further investigated the relationship between a C-terminal loop of TH-2PLD and PLD activities to elucidate the reaction mechanism and the recognition of the substrate. We have developed paper-based data collection forms that can be used to collect data from majority of entomological studies across multiple study areas using standardized data formats. Nitric oxide (NO) is produced from virtually all cell types composing the myocardium and regulates cardiac function through both vascular-dependent and -independent effects. During the past year, work was reported revealing new causes of childhood glaucoma and incredible new insight into the responsible genetic defects.

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Massive exudative retinal detachment following photodynamic therapy for retinal hemangioma in von Hippel-Lindau Syndrome. Microcomputerized tomograph for quantitative studies of bone in human extremities

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Evaluation of exposure to trihalomethanes in tap water and semen quality: a prospective study in Wuhan, China. DNA renaturations under nucleation-rate-limiting conditions on simple DNA such as bacterial and bacteriophage DNA show significant deviation from ideal second-order kinetics when followed by optical density measurements at 260 nm.

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ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics. Two small, randomized clinical trials have demonstrated clinically relevant benefit from folate treatment, which reduced HC in patients, compared to placebo. Distress was measured daily during treatment by the Daily Record Keeping Chart. Using care profiles as a catalyst for improving end of life commissioning, involvement and service delivery.

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Exhaled nitric oxide has been extensively investigated as a non-invasive marker of airway inflammation. From our case, we conclude that in GAMT deficiency language delay is not always more prominent than delays in other developmental areas. Couples complaining of sexual difficulties received both sex therapy and marital therapy in a balanced, cross-over design. Among the selected 498 genes, 44 genes are associated with neurotransmission, such as neuropeptides, their receptors, and vesicle transport, and 26 are ion channels regulating membrane potentials. This uncertainty is even more pronounced in patients who achieve very low LDL-C levels with statin treatment.

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The latter observations, which do not appear to have been reported previously, mean that false positives are to be expected if immunodiagnostic techniques are used for the recognition of malignant disease of the uvea, especially as smooth muscle antibodies can occur in non-neoplastic ocular diseases. Effects of soyasapogenol B, sophoradiol, and their glucuronides on the cytotoxicity of tert-butyl hydroperoxide to HepG2 cells.

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Differential nuclear staining assay for high-throughput screening to identify cytotoxic compounds. Often, ductal cells are present and at most show mild atypia but generally appear organized. Loss of chromosome 1p and 19q was assessed using fluorescent in situ hybridization with locus-specific probes.

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Natural peptide agonists of corticotrophin-releasing factor (CRF) receptors bind to the receptor by a two-site mechanism as follows: the carboxyl end of the ligand binds the N-terminal extracellular domain (ECD) of the receptor and the amino portion of the ligand binds the extracellular face of the seven transmembrane region. We provide an update on disease-associated titin mutations in cardiac and skeletal muscles and summarize what is known about the impact of protein-protein interactions on titin properties and functions. As GSH is the most abundant cytosolic reductant, we propose that its efflux may provide a non-oxidative mechanism by which the reducing environment of apoptotic cells is lost.

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Whether this has any effect on blood purines remains to be determined. S-100 protein as marker of the blood-brain barrier disruption in children with internal hydrocephalus and epilepsy--a preliminary study.

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Cis-acting intronic elements that regulate cartilage-specific alternative splicing of the type II collagen (Col2) pre-mRNA lie at or near splice site junction sequences flanking exon 2 of the gene. To investigate further, we established cells with forced expression of IL-6. In this article, the authors clarify the capability of three-dimensional ultrasound in different anatomic areas, and catalog its clinical merits in the early pregnancy to date. Isovalerate did not significantly affect the cellular levels of ATP and had no direct effect on N-acetylglutamate synthase activity. The prolonged half-life and high plasma sustained concentration of epidural ketamine might account for the difference in analgesic effects.

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Taken together the current literature indicates that, in addition to noradrenaline, other neurotransmitters and neuromodulators may regulate the tone of prostatic smooth muscle. Results were encouraging for affective functioning, but further research and development in this area is clearly needed. Tumor location of the lower-inner quadrant is associated with an impaired survival for women with early-stage breast cancer. Improvement in health status in the developing nations, especially in isolated rural areas, will hinge on changes in sanitation norms.

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Determination of styrene migration from food-contact polymers into margarine, using azeotropic distillation and headspace gas chromatography. Renal cysts usually are asymptomatic, produce no harm to the kidney and require no treatment once diagnosed. Until the initial report of the International Adjuvant Lung Trial in 2003, there was no real evidence from any individual randomized clinical trial (RCT) that adjuvant chemotherapy improves survival in resectable non-small-cell lung cancer.

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These data suggest that the functional gain and divergence of myogenic regulatory factors were driven by distinct positive selection of their transcription activation domains, whereas the function of the DNA binding domains was conserved in evolution. However, elevated levels of membrane cholesterol, such as have been observed in metabolic syndrome, interfere with CCK stimulus-activity coupling at the CCK1R, thereby disrupting this important servomechanism. We find that loss of RGS-3 leads to aberrantly increased G protein-coupled calcium signaling but decreased synaptic output, ultimately leading to behavioral defects.

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PEAKS is based on a speech recognition system and was extended to incorporate a speaker model. It became clear that this therapy corrected the malocclusion while improving facial. Thus, there was poor correlation between degree of polymerization and hardness.