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Panex (Paroxetine)
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Paroxetine

Panex is a selective serotonin reuptake inhibitor (SSRI) drug commonly known as Panex. It has a variety of uses, including the treatment of anxiety disorders, major depression, posttraumatic stress disorder, and symptoms of menopause, among others.26 It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham. A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. Because of its potent inhibition of serotonin reuptake, Panex is more likely to cause withdrawal effects upon cessation. Panex is well tolerated in most patients with a similar adverse effect profile to other members of its drug class. The controlled release formulation was designed to decrease the likelihood of nausea that is sometimes associated with Panex.

Other names for this medication:
Paroxetine, Aropax, Depaxil, Deroxat, Divarius, Motivan, Panex, Parocen, Parot, Parox, Paroxat, Paroxetina, Paxil, Pexeva, Sereupin, Seroxat, Xepar,

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Panex comes as a tablet, a suspension (liquid), a controlled-release (long-acting) tablet, and a capsule to take by mouth. The tablets, suspension, and controlled-release tablets are usually taken once daily in the morning or evening, with or without food. The capsules are usually taken once a day at bedtime with or without food. You may want to take Panex with food to prevent stomach upset. Take Panex at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Panex exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the liquid well before each use to mix the medication evenly.

Swallow the extended-release and regular tablets whole; do not chew or crush them.

If you are taking Panex tablets, suspension, or controlled-release tablets, your doctor may start you on a low dose of Panex and gradually increase your dose, not more than once a week.

Panex capsules contain a lower dose of Panex than is needed to treat depression and other forms of mental illness. Do not take Panex capsules to treat a mental illness. If you think you have depression or another mental illness, talk to your doctor about treatment.

Panex may help control your symptoms but will not cure your condition. It may take several weeks or longer before you feel the full benefit of Panex. Continue to take Panex even if you feel well. Do not stop taking Panex without talking to your doctor. Your doctor may decrease your dose gradually. If you suddenly stop taking Panex tablets, suspension, or controlled-release tablets, you may experience withdrawal symptoms such as depression; mood changes; frenzied or abnormally excited mood; irritability; anxiety; confusion; dizziness; headache; tiredness; numbness or tingling in the arms, legs, hands, or feet; unusual dreams; difficulty falling asleep or staying asleep; nausea; or sweating. Tell your doctor if you experience any of these symptoms when your dose of Panex is decreased.

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Overall, endocrine disruption by xenobiotics acting via AhR includes impaired cortisol biosynthesis and abnormal cortisol target tissue GR responses in rainbow trout. We conclude that the induction of myofibroblasts and the overdevelopment of capillary microvessels characterize the progression of lung fibrosis in SSc. Thirty local artists including ten governmental and non-governmental organizations actively participated.

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Comparative Evaluation of Fluoride Recharge Ability of Conventional and Hydroxyapatite Modified Glass Ionomer Cement with Daily Low Fluoride Exposure- An Invitro Study. Clinical information was obtained both at the time of diagnosis and at follow-up by reviewing the clinical history. Our study group included 20 children with refractory epilepsy, our control groups were composed of 20 children with well-controlled epilepsy and 20 healthy children. In linear regression models, poorer physical performance and more-limited sense of autonomy were independently associated with more restrictions in life-space mobility, explaining approximately one-third of the variation in life-space mobility. Since meiotic recombination is present in euchromatin, but absent in heterochromatin, it constitutes a key genetic property that can be observed transitioning between chromatin states.

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Structure-activity relations of water-in-oil vaccine formulations and induced antigen-specific antibody responses. Two full efficacy trials and 6 field trials with phoxim demonstrated good efficacy against 3 species of mites causing cattle mange.

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To maintain photosynthetic competence under copper-deficient conditions, the green alga Chlamydomonas reinhardtii substitutes a heme protein (cytochrome c6) for an otherwise essential copper protein, viz. Characterization of slow-gelling alginate hydrogels for intervertebral disc tissue-engineering applications.

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The aim of this study is to assess the morphological and hemodynamic cardiovascular changes of 24 high-level football players, using Doppler-echocardiography, and compare them to a similar control group. Type 3 finger length pattern, as an indicator of prenatal androgen exposure, was associated with having symptomatic knee OA, chronic pain, and hand OA. The lowest pH was recorded at the sites close to where the tablet had been placed.

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Recent evidence indicates that for lung cancer induction, combination of cigarette smoking and radiation exposure leads to risks that are not multiplicative but rather nearly additive. Mechanistic studies examining mitigated ROS production have been largely conducted in vitro, and the physiological significance of the findings is questioned. In solid tumors, chemotherapeutics must adequately diffuse through the extracellular compartment to achieve their cytotoxic effect.

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Bioengineered muscle grafts may be superior to synthetic materials for the surgical repair of LV scar. For both drugs, no correlation was observed between age and blood drug levels.

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Taken together, our results provide strong evidence that loss of AP-2 correlates with overexpression of PAR-1, which in turn contributes to the acquisition of the malignant phenotype of human melanoma. Establishing clinical criteria for burnout, as it is the case in some European countries, couldfacilitate the identification of the syndrome and the estimation of its prevalence in Italian work organizations. While limiting the fetal exposure to the harmful effects of depressant drugs, epidural anesthesia and/or analgesia improves placental perfusion and oxygenation of the fetus, which is beneficial, especially in conditions such as pregnancy-induced hypertension.

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Control of Inhibition by the Direct Action of Cannabinoids on GABAA Receptors. Obesity is, with rare exceptions, a complex phenotype resulting from interactions between environmental and genetic risk factor. Using a qualitative case study approach, data were collected from transplant recipients through organ-specific focus groups, from transplant coordinators and nurse practitioners through interviews, and from electronic documents. Relevance of endometrial pinopodes for human blastocyst implantation.

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A template based on positional residue frequencies in the N-terminal stretch of natural alpha-helical antimicrobial peptides was used to prepare sequence patterns and to scan the Swiss-Prot Database, using the ScanProsite tool. It is well established that androgen plays an important role in the pathogenesis of BPH in aging men. This work extends the current understanding about intradisciplinary conflict in the clinical realm. In the gemcitabine-resistant PANC-1 cells, a 48-h cotreatment with SAHA rendered the cells sensitive to the inhibitory and proapoptotic effects of gemcitabine.

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In this cross-sectional study, we performed at King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia from June 2000 to November 2002, a comprehensive evaluation including detailed eye examination, measuring circulating autoantibodies (antinuclear, antiphospholipid antibodies) and calculation of Systemic Lupus Erythematosus Disease Activity Index (SLEDAI). Furthermore, RV-B released less LDH than RV-A or RV-C, and induced lower levels of cytokines and chemokines such as CXCL10, even after correction for viral replication. The activity of Akt, the target of PI 3-kinase, decreased gradually after deprivation of serum, whereas it was rapidly reactivated upon serum stimulation.

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A retrospective review of 98 dogs undergoing thoracotomy over a five-year period was undertaken. HNE caused significant increases in expression of antioxidant enzymes, glutamate cysteine ligase catalytic subunit (GCLC), aldo-keto reductase 1C family member 1 (AKR1C1) and glutathione S-transferase-alpha4 (GSTA4).

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Altered gene expression within the nucleus accumbens (NAc), a ventral component of the striatum that receives substantial dopaminergic input, may play a role in some of the motivational aspects of opiate withdrawal. Collectively, these findings identify Id1 as a key mediator of PGE2-dependent modulation of radiation response and lend insight into the mechanisms underlying radiation resistance in GBM patients.

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The patient underwent a desensitization program consisting of plasma exchange (PEX), polyvalent intravenous (IV) immunoglobulins, and IV tacrolimus and mycophenolate mofetil (MMF). Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance.

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High serum POSTN levels are independently associated with increased fracture risk in postmenopausal women. Clinical and biochemical assessment of maintenance treatment in chronic recurrent seborrheic dermatitis: randomized controlled study.

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Modeling of a vapor-phase fungi bioreactor for the abatement of hexane: fluid dynamics and kinetic aspects. Objective : To determine the clinical and electroencephalographic characteristics of patients with Juvenile Myoclonic Epilepsy (JME).

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