This drug is used to treat high blood pressure. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: Losatan and hydrochlorothiazide. Losatan is an angiotensin receptor blocker (ARB) and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat heart failure.

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Neither daily nor extended administration of Sterilex Ultra was capable of maintaining an acceptable water quality in these older dental units. Five male and three female affected members of two autosomal dominant DURS2 pedigrees were enrolled in the study. The results indicate closely similar behavioural manifestations may arise by adolescence despite differences in speech development. beta-Blocker therapy is associated with clinically meaningful reductions in mortality and morbidity in patients with stable congestive heart failure and should be routinely offered to all patients similar to those included in trials.

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Processes of reactive microglia were conspicuous in low-grade HD, suggesting an early microglia response to changes in neuropil and axons and in the grade 2 and grade 3 cortex, were aligned with the apical dendrites of pyramidal neurons. Suppressed levels of serum cortisol following high-dose oral dexamethasone administration differ between healthy postmenopausal females and patients with established primary vertebral osteoporosis. At axon initial segments and nodes of Ranvier in neurons, the spectrin membrane skeleton plays roles in physically stabilizing the plasma membrane integrity and in clustering voltage-gated sodium channels for proper conduction of the action potential.

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Healthy subjects, including six men, five women between the ages of 18 and 35 years, and four women who were four to 20 years past menopause. Consequently, the tissue binding affinity of Gal-PEI complexes was 3.0-fold larger than that of native PEI complexes, suggesting the increasing of hepatic binding affinity much enhanced the hepatic gene transfection efficiency. We, therefore, studied -- in the same experiment from which the previous findings originated -- the effects of topiramate on the kinetic profile and hemodynamic response to methamphetamine. For regression analysis, data on prostate cancer incidence and mortality were obtained from the Texas Cancer Registry, while groundwater boron and selenium concentrations were derived from the Texas Water Development Board.

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The gene structure and expression of the Dfur2 gene of Drosophila melanogaster, which encodes the subtilisin-like serine endoprotease Dfurin2, was studied. uPAR expression induces multiple rapidly advancing protrusions that resemble the leading edge of migrating cells. Damage to biomolecules caused by oxidants, such as free radicals generated during metabolic processes, is widely recognized as a key contributor to somatic degeneration and the rate of ageing. This approach identified all of the major classes of platelet transmembrane receptors, including multitransmembrane proteins.

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In addition, growth rates of pld1 mutants in media with protein as the sole source of nitrogen were similar to growth rates of the wild-type, indicating that secretion of proteinases was not reduced. Human infection with Candidatus Rickettsia tarasevichiae (CRT) was first reported in northeastern China in 2012. European PH1 transplant registry report on the results of combined liver/kidney transplantation for primary hyperoxaluria 1984 to 1992. Interpreting the clinical relevance of results of IDT requires a thorough knowledge of the medical history, physical examination findings, and environment of each animal.

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The main electron ionisation induced fragmentation processes of fused norbornene analogues containing SiMe2 or GeMe2 and oxygen bridges, as well as their dependence on substitution, were investigated using mass (MS) and tandem mass (MS/MS) spectrometric analysis. S strains were also identified in archival tissues from paratuberculous sheep and cattle from Iceland, confirming epidemiological and microbiological evidence that paratuberculosis in Iceland was due to S strain following importation of infected sheep from Europe. The purpose of the study was to determine molecular changes in selected epithelial proteins in human keratoconus (KC) corneas compared to normal corneas.

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Furthermore the large latent complex, 125I-TGF-beta/LAP/LTBP-1 was able to bind to immobilized IGFBP-3. Second-order Hermite splines are used to model the received boundary in the neighboring blocks, while third order Hermite splines are used to model the missing boundary. Given the lack of major bleeding in this evaluation, fondaparinux could be a potentially safe treatment option for left ventricular assist device patients that are heparin-induced platelet antibody positive pending confirmatory testing results. None of our patients had total urinary incontinence or required a collecting device. In the light of the increasing incidence of Gram-positive infections on NICUs, antibiotic policies may have to be altered to accommodate these pathogens.

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Left carotid angiograms showed dural AVF of the transverse/sigmoid sinus fed mainly by the left occipital and posterior auricular arteries. This has caused concerns about whether CNTF is detrimental to the function of photoreceptors because it is considered to be a potential treatment for retinal degenerative disorders.

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Serum collected from SCID mice 1 hr after a 25-mg feed of OVA was unable to transfer tolerance of delayed-type hypersensitivity (DTH) into naive BALB/c recipients. M2-1 protein is found in nuclei of M2-1-expressing cells and in RSV-infected cells. Failure to find a humoral factor which influences the compensatory response after resection of the rat small bowel.

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Horses with preexisting lesions may be at greater risk of sustaining catastrophic injuries when exercised after treatment. Synthesis of hexagonal BaTa2O6 nanorods and influence of defects on the photocatalytic activity. The factors predicting dropout before program completion were divorce, use of cocaine and depressants, and living in foster care as a child. U-56,407 is active in vitro against Gram-positive bacteria but not Gram-negative organisms.

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Following this first hospital admission, all women were asked to switch the administration time from morning to bedtime or vice versa. American Gastroenterological Association medical position statement: Clinical use of esophageal manometry.

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The effect of MK-0524, a prostaglandin D(2) receptor antagonist, on prostaglandin D (2)-induced nasal airway obstruction in healthy volunteers. A literature search was conducted using the MEDLINE (1966-August 2004) and International Pharmaceutical Abstracts (1970-August 2004) databases with the search terms daptomycin, LY146032, and lipopeptide antibiotics.

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Loss of skeletal muscle during neoadjuvant chemotherapy is related to decreased survival in ovarian cancer patients. Meta-analysis of these trials does not support routine use of endotracheal intubation at birth in vigorous meconium-stained babies to reduce mortality, meconium aspiration syndrome, other respiratory symptoms or disorders, pneumothorax, oxygen need, stridor, HIE and convulsions.

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Group 1 included 4 eyes following extracapsular cataract extraction (ECCE) and rigid IOL implantation. to determine the number of measurements required to obtain stable bandwidth values for spatial frequency channels (SFCs) in the human visual system.

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MRI Appearance of Intracerebral Iodinated Contrast Agents: Is It Possible to Distinguish Extravasated Contrast Agent from Hemorrhage? However, the low positive predictive values reflect the weak correlations among these variables. Influence of dietary lipid and meal pattern on body composition and lipogenesis in adult rats. Concentrations of 14C drug in simian renal cortex and renal pelvis were up to 5 times plasma levels. Flagellar transcriptional regulatory factors have been demonstrated to contribute to V.

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Management of advanced glaucoma: Characterization and monitoring. The effects of serum calcium and parathyroid hormone and the interaction between them on blood pressure in normal subjects and in patients with chronic kidney failure. Quantification of chlorotyrosine and oxidized methionine in circulating HDL might be useful indicators of the risk of cardiovascular disease that are independent of HDL-cholesterol. Lower- and upper-limb muscle dysfunction was observed in COPD patients, irrespective of the presence of FFM depletion.

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Poxvirus DNA topoisomerase knockout mutant exhibits decreased infectivity associated with reduced early transcription. A combined molecular approach to phylogeny of the jumping spider subfamily dendryphantinae (araneae: salticidae). Inter-relationships among retrograde amnesia, post-traumatic amnesia, and time since head injury: a retrospective study.

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Taxonomical and morphological notes on two species of mudskippers, Periophthalmus walailakae and Periophthalmodon schlosseri (Teleostei: Gobiidae) from Singapore. Linguistic and cognitive abilities in infancy: when does language become a tool for categorization? Tenascin-R is expressed by Schwann cells in the peripheral nervous system. Traumatic separation of the proximal femoral epiphysis and fracture of the mid-shaft of the ipsilateral femur in a child.

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Clinical teaching fellows (CTFs) are doctors employed to teach, often undergoing a teaching qualification. Diagnosis and prognosis of lower respiratory tract infections: a cough is not enough. Treatment was comprised of cisplatin, teniposide, vincristine, doxorubicin, and cyclophosphamide during the first treatment period (1987-1991) or cisplatin and teniposide with alternating courses of ifosfamide and etoposide during the second treatment period (1992-2000). Gamma frequency oscillations are thought to provide a temporal structure for information processing in the brain.

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UHD is reliably diagnosed by an AChE reaction in native biopsy sections from the anocutaneous transitional zone and, potentially, from 3 - 4 cm above the pectinate line. MCPA is not alerting for likely genotoxic activity using established structure-activity relationship principles and it is concluded that, on the weight of evidence from the available data, MCPA is not genotoxic in vivo. After wide resection of the abscesses and fibrous body the heart was reconstructed with glutaraldehyde-fixed bovine pericardium. After a median follow-up of 12 months, 40 patients are alive, eight of whom have proven recurrence.

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Lignocaine decreased the incidence of all ventricular arrhythmias both during ischaemia and on reperfusion in a concentration-related fashion. For this study, an evaluation was conducted of the workshop given in Spring 1996.

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Our approach involved constructing a genealogy for this population and using a genealogic index to investigate familial aggregation. Characterization of residues and sequences of the carbohydrate recognition domain required for cell surface localization and ligand binding of human lectin-like oxidized LDL receptor. Mayaro virus infection alters glucose metabolism in cultured cells through activation of the enzyme 6-phosphofructo 1-kinase. The effect of weight loss on obstructive sleep apnea (OSA) severity and position dependence in the bariatric population. Dendritic cell networks were present only in follicular centers.

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Cloning of putative uncoupling protein 1 cDNA in a cold-intolerant mammal, the house musk shrew (Suncus murinus). Central nervous system tumor: advance imaging and multispecialty approach. To explore the potential mechanisms, we investigated the effects of RIC on coagulation and fibrinolysis. Oxytocin, with or without ergometrine, has thus been widely used with a recognized beneficial treatment effect. CONCLUSIONS: Our results suggest that a major contributing factor to decreased expression levels in T7 based systems is chromosomal mutation resulting in loss of functional T7 RNA polymerase.

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Validity was assessed by correlating the results derived with the outcome assessment systems with functional visual analog scale (VAS), aesthetic VAS, and manual activity questionnaire scores. But in vivo, compound 6a showed better results in inducing phase II detoxifying/antioxidative enzyme. An examination of jury verdicts for evidence of a similarity-leniency effect, an out-group punitiveness effect or a black sheep effect.

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With the intraarterial 133Xenon injection method, regional cerebral blood flow (rCBF) was measured from 35 regions of a cerebral hemisphere. Finally, evidence that, in spite of all negative blood cultures, Escherichia Coli via the urinary ways may be considered the aetiological agent is presented.

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The technique described is a safe, new, muscle-splitting, psoas-preserving, one-incision approach to provide access from L1 to S1 for multilevel anterior or oblique lumbar interbody fusion surgery. However, non-MHC genes are also crucial to arthritis development. Comparative Effects of Volutrauma and Atelectrauma on Lung Inflammation in Experimental Acute Respiratory Distress Syndrome. Isolation and identification of anti-platelet aggregation principles from the bark of Fraxinus japonica BLUME.

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Are urea and creatinine values reliable indicators of azotaemia in canine babesiosis? Hierarchical task analysis of Pathology PACS was classified into 17 tasks including 1) pre-operation, 2) text, 3) images, 4) medical record viewer, 5) screen transition, 6) pathology identification number input, 7) admission date input, 8) diagnosis doctor, 9) diagnosis code, 10) diagnosis, 11) pathology identification number check box, 12) presence or absence of images, 13) search, 14) clear, 15) Excel save, 16) search results, and 17) re-search. Finally, we characterized the potential role of the VIT gene in vision, which experienced positive selection and downregulated expression in the retina of the village chicken. Therefore, ointment should reasonably be chosen to adjust the moisture.

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After three months, the cement-blocked discs exhibited severe IDD, with the percentage of disc-height index (DHI), nucleus pulposus (NP) area, and NP T2 value significantly lower than the normal control. Synthesis and cytotoxicity of a novel iridoid glucoside derived from aucubin. A quantitative real-time PCR assay targeting the GroEL gene was developed to enumerate Neorickettsia sp. A randomized community intervention trial to increase awareness and knowledge of the role of periconceptional folate in women of child-bearing age.

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Parameters affecting the determination such as detection wavelength, sample injection volume and flow rate were studied and optimized. Direct evaluation via forced oscillation method of the electronic state density of sizable clusters. Eleven spots with matching mobilities (both M(r) and pI) to those identified in U937 were observed on 2D PAGE gels from human culture derived macrophages. A spectral dissociation constant, K(s) of 70 micromol litre(-1) was observed and an IC50 of 11 micromol litre(-1) was found for glyphosate inhibition of CYP71C6v1 P450 activity.

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Intragastric fermentation in patients with gastroparesis diabeticorum. Studies on the caloric reaction given by Fitzgerald and Hallpike.

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Pancreatic trauma is associated with high mortality and high incidence of complications. Stimulation of H1 or H2-receptor produces excitatory or inhibitory effects, respectively, on the smooth muscles and on the adrenergic nerves. Influence of Short-Term Octreotide Administration on Chronic Tissue Injury, Transforming Growth Factor beta (TGF-beta) Overexpression, and Collagen Accumulation in Irradiated Rat Intestine. The problem is complex, involving abuse and overuse of antibiotics (selecting for an increasing frequency of resistant bacteria), together with a lack of investment in discovery and development (resulting in an almost dry drug development pipeline).

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BRCA somatic mutations and epigenetic BRCA modifications in serous ovarian cancer. In 17 normal volunteers, the effect of blink rate on tear evaporation was assessed. Quantitative changes in permeability of rat lung epithelium in lung edema.

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Food and Drug Administration for the treatment of overactive bladder. Styles of inhibiting emotional expression: distinguishing repressive coping from impression management. Stroma-free hemoglobin increases blood pressure and GFR in the hypotensive rat: role of nitric oxide. Only one generic product was fully bioequivalent with the reference product Voltaren with regard to AUC, Cmax, and tlag.

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coli 23 s rDNA are more variable than the regions present in both prokaryotes and eukaryotes. Improvement in performance of SYN-DER lines compared with recurrent parents was not associated with a larger overall investment in root dry weight, but rather an increased partitioning of root mass to deeper soil profiles (between 60 cm and 120 cm) and increased ability to extract moisture from those depths. Estimates of the exposure rate at points near the source were obtained using analytical averaging.