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Lipibec (Atorvastatin)
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Atorvastatin

Taken together, Lipibec significantly ameliorated bleomycin-induced pulmonary fibrosis in rats, via the inhibition of iNOS expression and the CTGF (CCN2)/ERK signaling pathway. Efficacy and safety of extended-release niacin alone or with Lipibec for lipid profile modification

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Lipibec is used together with a proper diet to lower cholesterol and triglyceride (fats) levels in the blood. This medicine may help prevent medical problems (e.g., chest pain, heart attack, or stroke) that are caused by fats clogging the blood vessels. It may also be used to prevent certain types of heart and blood vessel problems in patients with risk factors for heart problems.

Lipibec belongs to the group of medicines called HMG-CoA reductase inhibitors, or statins. It works by blocking an enzyme that is needed by the body to make cholesterol, and this reduces the amount of cholesterol in the blood.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

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The value of serum drug assays in clinical practice is assessed, and it is concluded that, except in neonates, elderly persons or patients with hepatic and renal dysfunction, such assays are of little clinical value. This report examines the beneficial use of botulinum toxin in the treatment of ophthalmic disorders. The authors note that appropriate cooperation by scientists in various countries would make production of this antivenin an easy matter, and that the product could conveniently be distributed via PAHO or other international agencies.

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ORIGIN OF APOMICTIC RED ALGAE: OUTCROSSING STUDIES OF DIFFERENT STRAINS IN CALOGLOSSA MONOSTICHA (CERAMIALES, RHODOPHYTA)(1). Caspase activation occurs in a highly ordered cascade triggered by the initiator caspases 8 and 9, which activate the executioner caspase, caspase 3.

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Mercury adaptation among bacteria from a deep-sea hydrothermal vent. For those having a remission, an increase in the adequacy of social relationships and a decrease in rows was observed only in those who improved later on, at the 12-month interview. Although the trace-metal levels for some samples collected in highly industrialized zones approached or even considerably exceeded the upper WHO limits, the average concentrations of trace metals recorded in this study remained below critical values.

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Rectilinear bone scanning: differentiation between metastases and degenerative spinal disease. Genetic fingerprinting methods, such as repetitive sequence based-PCR (rep-PCR), have shown promise as BST tools but are time-consuming and labor-intensive. Reversible sideroblastic anemia associated with the tetracycline analogue COL-3. Correction: Standard HR.1.25, Element of Performance 1, for laboratory. Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation.

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Generation of phage particles displaying the fusion protein also requires superinfection of the host bacterium with a helper virus. Chinese hamster ovary (CHO) cells that express glycoprotein D (gD)-binding receptors are model cells that support a pH-dependent, endocytic entry pathway for all HSV strains tested to date. First, different immunological databases are described that maintain epitopes, antigens and vaccine targets.

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We examined whether this cohort differed in mortality rate and female-male mortality ratio compared with previous and subsequent birth cohort enrolled in the same trial. These patients either had hemorrhoids or incomplete mucosal prolapse.

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The excretion of p-chlorophenylmercapturic acid was markedly less than that of 4-chlorocatechol in humans who received monochlorobenzene orally or by inhalation. These results are not likely due to an impairment of neuromuscular transmission. There is a wide clinical spectrum of presentation and behavior ranging from a benign condition to an aggressive disease with a fatal outcome. The structures of the evolved-specificity caspase-7 (esCasp-7) revealed alternate binding modes for the substrate, including reorganization of an active site loop. We report the effect of a change to hospital ownership on the use of care management processes (CMPs) and health information technology (IT) among practices in the United States.

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With improvements to the broad-scale model component, the model synthesis approach and resulting tool could improve pest management strategy and provide a template for the development of spatially explicit pest pressure models. Treatment of highly potent and densely functionalized bryostatin analogue 1 with dimethyldioxirane afforded the C-9 hydroxylated hemiketal 2 via oxyfunctionalization of the C9-CH bond, one of 12 CH bonds geminal to an oxygen substituent in 1. 3-Hydroxyanthranilic acid oxygenase (3HAO) is the biosynthetic enzyme for quinolinic acid, an endogenous agonist of the NMDA glutamate receptor subtype and a potent neurotoxin. Real-time PCR based on TaqMan-MGB probe technology is an excellent method for detection of HBV DNA. By using this mutant as a magnifying glass of the structural effect of ligand binding, a comparative analysis of the binding of carbamoyl phosphate (CP) and analogs points out the crucial role of the amine group of CP in facilitating the transition toward the high-activity, high-affinity quaternary state.

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Vocal intensity in lecturers: results of measurements conducted during lecture sessions Polyamine enhancement of the synthesis of adenylate cyclase at the translational level and the consequential stimulation of the synthesis of the RNA polymerase sigma 28 subunit. Respiratory epithelial adenomatoid hamartomas and chondroosseous respiratory epithelial hamartomas of the sinonasal tract: a case series and literature review. This article describes the merits of 103Pd, a low energy x-ray emitter, as a new and potentially superior candidate for intraluminal brachytherapy. Prednimustine (Leo 1031), a conjugate of prednisolone and chlorambucil, was administered to humans and baboons and the metabolic fate of the compound ascertained.

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The capabilities of this computing scheme are demonstrated with five clinical examples and are related to the respective values of the classical Littmann formula as well as to enhanced methods described by Bennett (1988), Bennett et al. Neurologists are seldom involved with acute cerebrovascular care in the emergency department (ED), especially in patients with TIA.

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Thumb temperature in both groups rose with exercise but in the MHS subjects this rise was significantly delayed compared with the control subjects. Ratings of perceived exertion are not influenced by exercise stage of change in physically active college students. Palladium-catalyzed tandem alkenyl and aryl C--N bond formation: a cascade N-annulation route to 1-functionalized indoles. Biopsy results returned as metastatic adenocarcinoma, probably of prostate origin. Symptoms and diseases were classified according to the International Classification for Primary Care (ICPC-2).

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Patients with pulmonary tuberculosis develop pleural effusions with a high protein content. Direct conversion of mouse fibroblasts into induced neural stem cells. Patients who had glomerulitis and/or peritubular capillaritis on kidney biopsy performed 6 months after KT were enrolled. Volunteers were investigated twice, after their driving license examination and after a (stress-free) control session. The cause of death was metastatic disease due to uveal melanoma in 561 patients.

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The amino-terminal ubiquitin-like (ubl) domain is a proteasome-binding domain. Synthesis of adsorbents with dendronic structures for protein hydrophobic interaction chromatography.

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Self-imagination can enhance memory in individuals with schizophrenia. The elimination half-life is prolonged by two to four times in overdose, compared with that found in healthy volunteers given therapeutic doses.

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Transport of colloidal silica in unsaturated sand: Effect of charging properties of sand and silica particles. A novel approach employs attenuated mutant strains of Gram-positive and Gram-negative intracellular bacteria as carriers for the delivery of DNA vaccines. Smoking and implant location in the maxilla were associated with increased peri-implant marginal bone resorption. The metabolism of tissues from anaphylactically hypersensitive animals when antigen is added in vitrol. PFDA treatment also dose dependently decreased cytosolic, but not microsomal, glutathione S-transferase activity, and the activity of glutathione reductase was decreased by the highest dose of PFDA.

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Total score of all the five parameters, which was rated as effectiveness score, was calculated by using a standard scale. Human xylosyltransferase I (XT-I) initiates the biosynthesis of the glycosaminoglycan (GAG) linkage tetrasaccharide in proteoglycans. The course of optic tract fibres from small parts of the cat retina to the terminal projections in the dorsal lateral geniculate nucleus (dLGN) was demonstrated with anterograde tracer substances. The Web sites predominantly provide positive reinforcement and promotional information rather than the transparent disclosure of organ donation process.

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The authors begin by discussing the concept of bullying and sharing the types of bullying reported in two recent studies involving UK nursing students. To accomplish this goal, we review the current literature on medical errors and just culture, explain the dual process theory of cognition, identify common cognitive errors affecting neurosurgeons in practice, review cognitive debiasing strategies, and finally provide simple methods that can be easily assimilated into neurosurgical practice to improve clinical decision making. To examine whether prior application of the antioxidant vitamin C to the skin was able to reduce the cutaneous allergic response to PPD.

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A sensitive assay for the enzyme activity in hair follicles and epidermis that catalyses the peptidyl-arginine-citrulline post-translational modification. The 50:50 method for PCR-based seamless genome editing in yeast. We demonstrated the prevalence of hMPV subgenotype B1 circulating in Thailand during 2011.

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The association between orthodontic appliances and high levels of Streptococcus mutans and Lactobacillus spp was assessed with logistic regression models, taking age, sex, pH and buffer capacity into account. Our study suggests that the magnetic moment of Er(trensal) can be stabilized via suppression of quantum tunneling of magnetization by exchange coupling to the Ni surface atoms. This suggests that lessons learned in this area may be directly applicable internationally. Dose efficiency of erythropoiesis-stimulating agents for the treatment of patients with chemotherapy-induced anemia: a systematic review.

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The residuals of traumatic injuries from home or workplace accidents, automobile accidents, physical assault, or other unintentional human error can affect victims both physically and psychologically. These results support the immunocompetence-handicap hypothesis for male faces in that masculine traits signalled health during adolescence. It appears also that the melatonin signal is decoded in the pituitary, probably involving the short loop negative feedback of LH on LH-RH hormones. Health and safety issues related to such working activities are considered as relevant to workers as well as to the general public. Efforts to prevent cyberincivility can be achieved through focused education on cybercivility, development of clear policies related to its consequences, and formulation of guidelines for both student and faculty behavior online.

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Microarray analysis of seminiferous tubules isolated from XX/Sry testes confirmed the missing expression of several Y-linked genes and the alterations in the expression profile of genes associated with spermiogenesis. This complicates the ability of fine-mapping to identify a small set of SNPs for further functional follow-up. The empirical-observing and the communicative-participating view.

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Reservoirs have the potential of enhanced quality fish production. With the present concept these patients benefited from a less invasive procedure (1 surgical procedure and no grafting) and immediate rehabilitation (prosthesis attached directly after surgery). The aim of this study was to evaluate the distribution of aFGF and FGFR4 in specific cell types of fibroadenomas to understand their possible role in the growth of these breast lesions. A miniature recessed (i.e., cup) surface EMG electrode intended for use in the perioral region during speech has been constructed and tested. gluamicum has a peculiar sugar transport system involving fructose efflux after hydrolyzing sucrose transported via sucrose EII.

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The application of models requires knowledge of their accuracy and limitations. However, the contribution of neurons and glial cells to total brain cholesterol metabolism is unknown.

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Tumor-promoting 12-O-tetradecanoyl-phorbol-13-acetate and phorbol-12, 13-di-decanoate, but not the non-tumor-promoting 4alpha-phorbol-12, 13-di-decanoate, stimulated deacylation of cellular lipids, prostaglandin biosynthesis, and morphological changes in cultured MDCK cells. Follow-up of four patients supports the view that amyloidosis associated with psoriasis is an aggressive disease that may be fatal.

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We report the experimental observation of a submicron cellular structure on the surface of silicon targets eroded by an ion plasma. Based upon aberrant segregation of glutamate pyruvate-transaminase (GPT) and reduced enzyme activity on electrophoresis, seven new families with a GPT null allele were identified during genetic linkage analysis for a number of different traits.

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Unilateral combined transections of the fimbriafornix and angular bundle in adult Fischer 344 rats were used to study the effects of deafferentation on hippocampal expression of calretinin, calbindin D-28k, and parvalbumin. Estrogen stimulates estrogen-related receptor alpha gene expression through conserved hormone response elements. These cells became larger and increased in number after the 8th week.

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Inhibition of nuclear factor kappaB (NF-kappaB) translocation to the nucleus blocks the effect of TNF-alpha on AQP5 expression, indicating that activation of NF-kappaB is required, whereas inhibition of extracellular signal-regulated or p38 mitogen-activated protein kinases showed no effect. Data analysis was conducted according to the standards of the Neonatal Cochrane Review Group. The technique enabled visualization of structures to our knowledge not previously described on cross-sectional imaging: the individual layers of the esophageal wall, the thoracic duct, a connective tissue layer attaching the esophagus to the anterior wall of the aorta, and a fascial plane passing between layers of the right and left parietal pleura posterior to the esophagus.

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Multi-modal combination gene therapy for malignant glioma using replication-defective HSV vectors. Cartilage explants were cultured with estrogens with or without recombinant bovine insulin-like growth factor-I (IGF-I).

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The remaining 1,229 incidents involved nondependent patients who had taken a drug overdose, and these cases were distributed more evenly between hospitals all over the Greater London area. Matrilin-4 was first observed at day 7.5 post-coitum in mouse embryos. We exchanged and deleted the N termini of two such siderophore receptors, FepA and FhuA, which recognize and transport ferric enterobactin and ferrichrome, respectively. Obesity is a multifactorial disease of epidemic and global proportions that poses the most significant threat to the health of our younger generations.

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The activities of both hepatic ornithine decarboxylase and hepatic ornithine decarboxylase antizyme were measured at intervals of hours after the injection of thioacetamide. Monensin increased irreversible losses of glucose from 582 to 677 g/day for the high-grain diet. The stone expulsion rate, time to stone expulsion, analgesic use, number of hospital visits for pain, follow-up and endoscopic treatment, and adverse effects of the drugs were noted.

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In the MGG8 model, which displays a low degree of vessel abnormality, A2V induced no significant changes in the tumor vasculature but still prolonged survival. High tween concentrations in the culture medium caused a reduction of the bacterial virulence. Since mfd codes for a transcription-repair coupling factor, this transcription-coupled repair system evidently becomes operative downstream of the initiation complex region in vivo. Survival after 10 min exposure to 50, 60, 70, 80, 85, 90 and 95 degrees C in culture medium and in orange juice was also assessed.

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With the implementation of competency-based assessment systems, it will become important to determine which attributes actually promote the development of competence among learners, thereby allowing the encouragement of those attributes. Most of these sequences were identified as ACS but three of them, belonging to the mammalian species, were annotated as another gene named: the SA gene, which is involved in the essential hypertension. The scalp as a site of tumoral calcinosis has not been previously reported in adults. hfaC was not required for holdfast attachment or binding to surfaces.

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Sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) for the identification of hypertension were assessed for different thresholds of BPHR. Recent research has emphasized the value of antidepressants especially the selective serotonin reuptake inhibitors, benzodiazepines, and related sedative-like compounds. Implications of this investigation for conceptualization of TM are discussed. HOXB9 may play an important role in the invasion and metastasis of colon cancer cells and may be a useful biomarker for metastasis and prognostic of colon cancer. In this report, two cases with spontaneous regression of osteochondromas are presented.

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Role of lipid rafts in trimeric G protein-mediated signal transduction To assess the reliability and validity of an instrument to measure behavioral competences in HIV/AIDS-infected persons. Shoulder function depends on a balance of forces from muscles, ligaments and articular cartilages, as well as inertial, gravitational and aerodynamic loads on the wing.

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Vaccination of Syrian hamsters with a single dose of the rVSV vaccine vectors resulted in strong humoral immune responses with neutralizing activities found only in those animals vaccinated with rVSV expressing NiV G or F proteins. Expected distributions of root-mean-square positional deviations in proteins. blavin dentist reviews Glycosylation of human trophoblast integrins is stage and cell-type specific. Cox regression was used to estimate the association between predictors of interest and first diagnosis of UGIB. An isosparteine derivative for stereochemical assignment of stereogenic (chiral) methyl groups using tritium NMR: theory and experiment.

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