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Cryofaxol (Cyclophosphamide)
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Cyclophosphamide

Cryofaxol is the generic name of the prescription drug Cryofaxol, a chemotherapy drug for people with certain cancers. It’s prescribed for non-Hodgkin lymphoma, Hodgkin lymphoma, multiple myeloma, small-cell lung cancer (SCLC), leukemia, ovarian cancer, retinoblastoma, neuroblastoma, and breast cancer. Cryofaxol is sometimes used to treat kidney damage. Doctors may also prescribe Cryofaxol off-label to treat some kidney infections; systemic sclerosis or scleroderma (hardening of the organs and body tissues); and juvenile arthritis. The Food and Drug Administration (FDA) approved Cryofaxol as Cryofaxol in 1959, and Baxter International, Inc. manufactures it.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Cryofaxol injection comes as a powder to be added to fluid and injected intravenously (into a vein) by a doctor or nurse in a medical office or hospital outpatient clinic. It may also be injected intramuscularly (into a muscle), intraperitoneally (into the abdominal cavity), or intrapleurally (into the chest cavity). The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer or condition you have.

Your doctor may need to delay your treatment or adjust your dose if you experience certain side effects. It is important for you to tell your doctor how you are feeling during your treatment with Cryofaxol injection.

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Evaluation of a lysostaphin-fusion protein as a dry-cow therapy for Staphylococcus aureus mastitis in dairy cattle. MP2 Study of Physisorption of Molecular Hydrogen onto Defective Nanotubes: Cooperative Effect in Stone-Wales Defects.

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In some cases, like locomotion, the mechanics of the body dominate in determining the energetically optimal course of action. To examine the effects of acute CM supplementation on grip strength, vertical power, and anaerobic cycling performance in female, MA tennis players.

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Uricotelism in the common Indian apple-snail, Pila globosa (Swainson). Taken together, we have identified a previously unrecognized proteolytic truncation of integrin beta4 generated by caspases that disrupts key structural and functional properties of epithelial cells and promotes apoptosis.

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Methotrexate-immobilized poly(ethylene glycol) magnetic nanoparticles for MR imaging and drug delivery. Eight malaria patients (all male, mean age 22 years) confirmed to be infected with Plasmodium vivax underwent (99m)Tc-GSA liver scintigraphy, followed by liver ultrasonography and (99m)Tc-colloid scintigraphy using phytate within 3 days. Although chronic administration of 5-HT1A drugs appears necessary for clinical anxiolytic and antidepressant activity, the most noteworthy neuropharmacological effects in animals seem to occur in 5-HT2 and, perhaps, 5-HT3 receptors which are downregulated.

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High pressure induces an irreversible aggregation of the ferrous deoxy alpha-chains, whereas the AHSP/alpha-Hb complex shows reversible hexacoordination of the alpha-Hb without protein aggregation. Since RA acts by nuclear receptors which directly regulate gene expression, we postulate that the primary targets of RA action in this system are genes which are regulated early in adipose conversion. This paper presents the results of an ethnographic study using case study and educational criticism to explore mental health classrooms and share practical approaches to teaching. We then calculated yearly rates of potential DDIs in continuously enrolled members aged 19 and older from 1998 through 2001.

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Heart rate and eye movements were obtained to assess the attentional processes associated with this cognitive bias. Electrochemical therapy--comparison with other local treatment methods on rat model. In all other ways, participants received their usual intrapartum care. These observations support the idea that humans have cells that resemble MNTB neurons in other species. Retrospective analysis by data processing tools for comprehensive two-dimensional gas chromatography coupled to high resolution time-of-flight mass spectrometry: a challenge for matrix-rich sediment core sample from Tokyo Bay.

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ATPgammaS was found to substitute for ATP in all pairing reactions examined. Validation of the ANSR Listeria method for detection of Listeria spp. The aim of this study was to demonstrate how, in combination with auditory evoked potentials, this system can be used with satisfactory results for universal screening of all live births.

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DNA was labeled by nick translation with 35S and used as a probe in Southern- or colony-blot DNA hybridization. Caring for a mentally ill relative demands effective coping strategies. In response to vascular injury, adventitial fibroblasts can modulate their phenotype to myofibroblasts, cells that participate in arterial remodeling. The vps-dependent and -independent biofilms differ in their environmental activators and in architecture. Silencing of hepcidin enforces the apoptosis in iron-induced human cardiomyocytes.

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Using the telomeric repeat amplification protocol, it could be demonstrated that cultured, proliferating benign mesothelial cells may present a weak telomerase activity, as is known in other benign cells including activated lymphocytes. Large incisional hernias surgery with the use of non-adherent mesh Multilength Scale Patterning of Functional Layers by Roll-to-Roll Ultraviolet-Light-Assisted Nanoimprint Lithography. Genetic and biochemical approaches to individual sensitivity to drug preparations 6275 autopsies performed at the Institute of Pathology of the University of Zurich in the period 1973--1976 included 47 microscopically verified cases of thrombotic endocarditis.

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Circulatory levels and activities of MMP-2 and MMP-9 in patients with T1DM were significantly higher than those in control subjects. Reverse total shoulder arthroplasty with structural bone grafting of large glenoid defects. Of these 30 patients, 16 had preoperative haemodynamic investigations. Heme oxygenase-1 (HO-1) is a stress-responsive enzyme that acts during inflammatory reactions as the rate-limiting step in the catabolism of heme, yielding equimolar amounts of iron (Fe), biliverdin, and the gas carbon monoxide (CO).

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Changes of the trigeminal nerve in experimental neuro-paralytic keratite After incubated with STAT3 inhibitor Cucurbitacin I or CXCR4 antagonist AMD3100, the apoptosis of AML cells induced by mitoxantrone was evaluated. Disadvantages include increased cost and prolonged operative times.

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In the particular case of plant plasma membrane aquaporins (PIPs), PIP1 and PIP2 monomers interact to form heterotetramers. Exogenously applied GSNO (20-50 nM), SNAP (2-4 nM) and hydroxylamine (300-600 nM) caused relaxations that did not decline during the passage down the cascade. This preliminary investigation clearly shows the feasibility of high frequency ultrasound imaging to study chick embryo development in a longitudinal and noninvasive fashion.

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However, a clear-cut demonstration of a direct and specific effect on mnemonic processes has not yet been offered. The results suggest that both HSP25 and alphaB-crystallin have the potential to inhibit actin polymerization and that this activity is regulated by phosphorylation. MR60 induces a sugar selective aggregation of beads coated with glycosylated albumin: beads bearing alpha-D-mannosyl residues are aggregated while beads bearing alpha-D-glucosyl residues are not. We used a Drosophila model of human tauopathies to investigate the role of oxidative stress in neurodegeneration.

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These results suggest that sesamin inhibited LPS-induced IL-6 production by suppression of p38 MAPK signal pathway and NF-kappaB activation. The structure and kinetics support the hypothesis that the bridging oxygen atom initiates hydrolysis.

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Transversus abdominis plane block is effective method with convenient technique, drug dosage, and volume in pediatric patients undergoing inguinal hernia surgery. There has been neither mortality nor complications in the 13 cases of arterial and venous splenorenal anastomoses that we have done with this method. FSH induced a dose-dependent increase in both estradiol production and P450 arom mRNAs levels with a much more enhancement in the full-length mRNA. NRP was achieved by cannulating the aorta and vena cava after death.

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The telomeric repeat amplification protocol (TRAP assay) was modified using electrophoresis and staining with SYBR-green I to detect telomerase activity in a range of 10 to 10(7) parasites. The first known example of this rare tumor occurring in the testis is reported. To assess the effectiveness, local safety and tolerability, and systemic pharmacokinetics of two topical PDE4 inhibitors, roflumilast and TAK-084, in plaque psoriasis. The Americas have set a goal of interrupting indigenous transmission of measles using a strategy developed by the Pan American Health Organization (PAHO). An experimental study was designed to determine the minimum inhibitory concentration (MIC) of Pineapple extract per se and in conjunction with vancomycin.

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Downregulation of HDAC9 inhibits cell proliferation and tumor formation by inducing cell cycle arrest in retinoblastoma. Prognostic significance of opioid use in the active treatment of advanced colorectal cancer. Distance of the osteotomy to the first MTP joint has no relevance with the repair of the deformity. Future developments of the lens type should include PCO-reducing factors, such as sharp edge optics and foldable materials. These results indicate that mAb dimer fractions are rather complex and may contain more than one kind of dimer.

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Communicating about obesity and weight-related topics with children with a physical disability and their families: spina bifida as an example. The present study reports that tDCS applied to the left dorsolateral PFC (dlPFC) shaped accuracy of episodic memory via polaritiy-specific modulation of false recognition. Candidates were selected at first with conventional transrectal random prostate biopsies. The A3243G mutation was detected in the patient and maternal relatives (mother and siblings, all of them asymptomatic).

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This is probably due to the use of low-resolution detection methods. Effects of severe prior exercise on assessment of maximal oxygen uptake. The internal structure and validity of terms used in the Brief Psychiatric Rating Scale (Overall and Gorham, 1962) was analyzed. In postmenopausal women, risk is primarily increased by sequelae of lower estrogen levels. Associations of pemphigus and autoimmune disease with malignancy or thymoma.

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This paper provides a rationale for phenotyping COPD and describes the methodology of a large study in CEE. Ridol and the combination Atropin-Promedol-Pipolphen proved to have a specific lymphotropic affinity. The expression of these proteins often fluctuates and thereby causes individual pharmacokinetic variability. Although graft rejection mediated by host immune cells and GVHD mediated by donor immune cells can be prevented or mediated by immune suppression therapy, genetic HLA matching remains essential for successful strategies designed to minimize the risks of transplantation. Repetitive transcranial magnetic stimulation (rTMS) is a widely-used method for modulating cortical excitability in humans, by mechanisms thought to involve use-dependent synaptic plasticity.

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Very low amounts of ascorbic acid modify alkaline phosphatase fluorescence, absorption and enzymatic activity. In a cell-free approach, fatty acids were added directly to cell lysates, and we confirmed that increasing fatty acid unsaturation correlates with increased inhibition of telomerase activity. Quantitative phase: survey with a questionnaire developed from the features identified in the qualitative phase.

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Palladium-catalyzed inter- and intramolecular coupling reactions of aryl and vinyl halides mediated by indium. These results indicate that residues in TMs 4, 6, 10, 11, and 12 must contribute to the binding of verapamil. Using nanoindentation, the 22 different samples had reduced modulus values ranging from 840 MPa to 4.14 GPa.

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Platelets were removed from 25 patients with leukemia during remission and were frozen for subsequent transfusion. Reaction Mechanism of Guanosine Triphosphate Hydrolysis by the Vision-Related Protein Complex Arl3-RP2. Growth factors bind to their specific receptors on the responsive cell surface and thereby initiate dramatic changes in the proliferation, differentiation, and survival of their target cells. A subset of thalamocortical projections to the retrosplenial cortex possesses two vesicular glutamate transporter isoforms, VGluT1 and VGluT2, in axon terminals and somata.

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Split liver and living donation liver transplantation: the Berlin experience. P50 suppression was measured using paired clicks with 500-msec interstimulus intervals.

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A precise mapping within the region from 23 to 35 kDa by using a combination of narrow overlapping fractions and purified proteins enabled the identification of the 24-kDa antigen MPT64 as a molecule specific for tuberculous infection. Determinants of response to immunosuppressive therapy in idiopathic pulmonary fibrosis.

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Investigations of the mechanistic dichotomy between two catalytic systems are also presented. Estimates of innervation density verify the long-standing assumption that innervation density is greater for foot and toes than for proximal hindlimb, at least for low-threshold cutaneous myelinated afferents.

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Data obtained in REC animals showed that 1 week of recovery allowed the restoration of a good locomotor performance. The present study was undertaken to compare drug continuation rates between the first course and second course of anti-TNF therapy. The data were derived from a large and representative population-based sample.

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A novel approach is presented that allows high-quality, 3D patterned bionanocomposite layered films to be constructed on substrates whose surface properties are incompatible with existing self-assembly methods. Efficient segregation of the low copy number plasmid mini-F is dependent on partition functions encoded by the plasmid sopABC genes.

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An ultrastructural investigation of muscle attachment in the opercular filament of a polychaete annelid. The results showed that rosmarinic acid oxidation was almost totally dependent on the presence of H2O2 and protein, and that brownish products were the results of this oxidation, resembling those shown by aging cell cultures. Recent peritonitis and antibiotic therapy are associated with a poor treatment response.

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In comparison with the contrast germanium wafer, the dye-binding germanium wafers showed that the intensity of the first grade Raman peak of the germanium substrate was reduced and some new Raman peaks corresponding to the dyes appeared from 600 to 3,200 cm-1. Although the BCR domain of p85 binds Rac, the effects of the p85 constructs were not because of a general inhibition of Rac signaling, because sorbitol-induced JNK activation in MTLn3 cells was not inhibited.

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The reliability of dermatological teleconsult is very high, especially for tumoral or infectious diseases. Work restructuring: the process of redefining roles of patient caregivers. Modifications of the cuticular hydrocarbon profile of Apis mellifera worker bees in the presence of the ectoparasitic mite Varroa jacobsoni in brood cells.

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Given the high prevalence of diabetes, the high proportion of patients potentially not identified with a selective acihexal 200mg to ml screening in this study and the relatively low cost, universal screening for gestational diabetes seems the best way to identify patients and prevent adverse obstetrical and neonatal outcomes. Repair of dyskinetic or akinetic left ventricular aneurysm: results obtained with a modified linear closure. The apoprotein alterations were consistent in incubations in which the triglyceride concentrations varied from 330 mg/dl to 4200 mg/dl, and were not affected by inhibition of the Lecithin:Cholesterol Acyl Transferase (LCAT) reaction in the incubation mixture. We, therefore, determined adrenal gland volume in patients with major depression before and after treatment and in matched normal controls, and compared adrenal size with functional indexes of pituitary-adrenocortical activity. Related experimental work in which a bench top aneurysm model is developed is also discussed.

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The functionalized diarylzinc reagents were prepared via an iodine/magnesium exchange of the corresponding aryl iodide followed by transmetalation of the resultant Grignard species with ZnCl(2). The Project achieved its aim to develop diazole drug addiction a strategy to improve services for people with comorbid psychosis and problematic substance use. We describe the valuable role of intraoperative transesophageal echocardiography in the detection of immediate prosthetic valve dysfunction.

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Potential risk factors for the development of complications were also analyzed including site and nature of the lesion, presence of portal hypertension, and number of needle passes. Similarity to high molecular weight actin-binding protein in macrophages, platelets, fibroblasts, and other tissues. Further studies of the possible mechanism behind this association are needed. The various situations involving the criminal where potential problems may exist are reviewed according to the general problem areas of precustody, custody, and postcustody. Performance was assessed through monitoring membrane flux, transmembrane pressure, effluent biochemical oxygen demand, and operational cost of the experimental system while treating abacavir sulfate and lamivudine tablets for children filtered secondary, secondary, and filtered primary effluents.