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Mitotic entry in the pim1-d1ts mutant is normal, but mitotic exit leads to the accumulation of cells arrested with a medial septum and condensed chromosomes. Reflux in the lower segment ureter was treated in 13 patients and upper segment ectopia or ureterocele was managed in 3 patients with this operative procedure. This effect was accompanied neither by enhanced radical generation nor lipid peroxidation and was not attributed to apoptosis.

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Toward this end, data are summarized which demonstrate that laboratory animals will work substantially harder and prefer to work under gambling-like schedules of reinforcement in which the number of responses per win is unpredictable. One novel form of immunotherapy is the use of cancer vaccines consisting of tumor cells genetically engineered to secrete cytokines. Expression of antigen CD40 and survivin gene and their clinical implications in acute myeloid leukemia

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A comparative electron microscopic and morphometric investigation of lymphocytes has been performed. Eating disorders concurrent with type 1 diabetes: pathology and management HCC patients who underwent LT between 2000 and 2010 were evaluated.

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The role of epigenetic modifications in cardiovascular disease: A systematic review. Measurements of nociceptive reflex threshold to pressure and heat were made and then repeated after intraperitoneal injection of saline or one of three doses of levetiracetam (100, 200, 500 mg/kg). The glycosphingolipid monolayers studied had various surface potentials according to the complexity of the polar head group of the lipid. Early changes of endometrial neoplasia revealed by loss of mismatch repair gene protein expression in a patient diagnosed with Lynch syndrome.

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Haptens, prohaptens and prehaptens, or electrophiles and proelectrophiles. However, impaired immune functions may lead to reactivation of BK virus. Two-dimensional analysis of serum and tissue proteins: multiple gradient-slab gel electrophoresis. Corn steep liquor powder could be considered a feasible and inexpensive alternative to yeast extract as a nitrogen source.

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Studies using fMRI have demonstrated that visual stimuli activate auditory cortex in deaf subjects. Analysis of clinical decision support system malfunctions: a case series and survey. MAPK pathway inhibition enhances the efficacy of an anti-endothelin B receptor drug conjugate by inducing target expression in melanoma. In multivariate linear regression models with height, lean body mass, fat mass and trunk-to-limb fat mass ratio as predictor variables, lean mass was uniquely associated with the largest proportion of variance of TBBMC and TBBMD in males (semi-partial R(2) 0.275 and 0.345, respectively) and TBBMC in females (semi-partial R(2) 0.183).

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Insights Into the Allosteric Inhibition of the SUMO E2 Enzyme Ubc9. Tetraploidization and progressive loss of 6q in a squamous cell carcinoma of the parotid gland. Records of horizontal components of unsteady fixation by amblyopic eyes were characterized by abnormally large saccades and a nasalward bias for slow drifts.

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There is an unreasonable delay in the investigation of alleged child sexual abuse. A quantitative analytical method for the determination of a new anxiolytic (CGS 19480A) in human plasma using high performance liquid chromatography. The author presents a variety of techniques and the rationale for the use of plantar foot incisions, along with discussion on the prevention of complications. Unusual effect of adrenalin and tetraethylammonium bromide on return circulation The highest doses of the respective drug, 80-160 micrograms of DA and 20-40 micrograms of l-NA, produced stimulation of the locomotor activity at a later time interval (6-9 min).

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Effect of dosage form and formulation factors on the adherence of drugs to the esophagus. Dodecyl acetate is the first repellent allomone identified in bumblebees.

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Influence of the legislation on the advertisement of psychoactive medications in Brazil. After classification of the metatypical carcinoma into the group of basalioma tumors similar computertomographic patterns of different origin are pointed out. However, it was the difficult confirming the diagnosis by spinal MR imaging, and the negative result of the first MR examination (performed 5 weeks after manifestation of first clinical symptoms of the disease) delayed surgical treatment. The application of an auditory apperception test to clinical diagnosis. Enzyme immobilization on silane-modified surface through short linkers: fate of interfacial phases and impact on catalytic activity.

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A total of 256 Dutch community pharmacies were selected, based on the dispensing of 11 undesirable interacting drug combinations between January 1st, 2001 and October 31st, 2002. Complementary deoxyribonucleic acid expression arrays were used to screen for busulfan responsive genes in ECV304 cells. Restriction enzymes are essential reagents to molecular biologists, but their relevance to bacterial populations is less obvious. Evaluation of a New Needle Guidance System for Ultrasound: Results of a Prospective, Randomized, Blinded Study.

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Some of the changes did not increase appreciably after 8 months of exposure, whereas others continued to increase as a function of cumulative exposure. Animal models of sustained AF have been developed primarily in the short-term setting. Screen-based compensatory tracking task software includes a tracking ball (operated by the joystick) which moves randomly in all directions, and a second tracking ball which moves horizontally (operated by the rudder pedals). Among three y genes in the operon, deletion of the yabQ gene, which is predicted to encode a protein product of 468 residues with five membrane-spanning domains, resulted in a large decrease in numbers of chloroform-, lysozyme- and heat-resistant spores, compared to findings with the wild-type strain. To study whether digital examination preceding anal manometry causes significant alteration of maximum resting pressure reading and to quantify the discrepancies, 78 individuals (64 incontinent, 14 controls) were investigated.

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Feeding of DFA III increased net Ca transport and LY passage in the cecal but not in small intestinal or colonic epithelium. The patients suffered from a basic angiology disorder in arteries of lower extremities.

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The implantable monitoring device REVEAL protracts significantly the monitoring period. Three F3 populations were used to map Pm3h in Abessi, Pm3i in line N324, and Pm3j alleles in GUS 122 relative to microsatellite markers. Glioblastoma multiforme show large amounts of active Ras, considered an appropriate target for directed therapy. Laboratory professionals must be prepared for professional, civil justice, and social impact in the event of a future major bioweapons event.

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The subjects were evaluated before and after attending specified instructions of 15 min duration and after a period of 6 months. The goal of this study is to identify characterization of expressed sequence tag (EST)-simple sequence repeats (SSR) markers from EST library of durum wheat and functional analysis of SSR-containing EST sequences for application in comparative genomics and breeding. These results indicate that prolactin urinary excretion in children with renal disease is dependent on the renal proximal tubular function.

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Psychosocial and psychodynamic factors influencing health care utilisation. We assessed the validated communication skills attitude scale among medical residents from different rotations. Coronin is an actin-binding protein, which contains WD (Trp-Asp) repeats and a coiled-coil motif, and plays a role in regulating organization of the actin cytoskeletal network. This hypothesis is consistent with their sporadic distribution within Rhodophyta.

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It is now being recognised that dietary antioxidants, in particular vitamin E, will play an important role in designing future strategies. Congenital tricuspid insufficiency is a rare disease secondary to malformations of the tricuspid valve and their chordae tendinae. Recent work has shown that collectins have roles in resistance to allergy and in the control of apoptosis and clearance of apoptotic macrophage in the lung. We detected viruses that were entirely (8 of 8 genomic segments) of American lineage, viruses that were entirely of Eurasian lineage, and viruses with mixed American-Eurasian lineage.

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FDG PET for imaging pericardial manifestations of Hodgkin lymphoma. In a previous study, we developed a clinical decision aid for identifying all patients undergoing resuscitation who survived to hospital discharge.

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Up to date there is a narrow and broad interpretation of the term biological safety (BS) the world over. Indeed, recent in vitro data from studies on endothelial cells, monocytes-macrophages and smooth muscle cells support a direct role for CRP in atherogenesis. PROCEEDINGS of the Physiological Society of Philadelphia, session of January 20, 1953.

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The CPMV-based systems have advantages over existing plant expression systems in terms of the expression levels obtainable and the simplicity and flexibility of use, and should be of great practical benefit in the development of plants as bioreactors. Positive responses to keeping Florence Nightingale as the symbol of nursing. This study compared the tumor characteristics of patients with HCC within the Milan criteria treated by resection or transplantation, and elucidated their impact on long-term survival. Directed deprotonation-transmetalation as a route to substituted pyridines. Formation of stable complexes between the triazine units and (R)-3-methyladipic acid has also been investigated by means of NMR diffusion-ordered spectroscopy (DOSY) experiments in chloroform.

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Contralateral retinal afferents in the DRN appeared to terminate primarily in the dorsomedial and lateral subdivisions of the DRN, and a less extensive ipsilateral component also was observed. FGF-2 may underlie in the action of EMD on osteoblasts during periodontal regeneration.

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Macrophage inflammatory proteins 1 alpha and beta (MIP-1 alpha and beta) and macrophage inflammatory protein 2 (MIP-2) are approximately 6-8 kd, heparin binding proteins that exhibit a number of inflammatory and immunoregulatory activities. Determinants of locus of control orientation in male alcoholics. The yin and yang of adaptive immunity in allogeneic hematopoietic cell transplantation: donor antigen-presenting cells can either augment or inhibit donor T cell alloreactivity.

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However, the relative rate of transcription of the DHFR gene changes very little during this period. The increased responses to endothelin-1 of some variables in the hypertensive animals may involve structural changes in the resistance vessels. These results suggest similarity of the regulatory mechanisms in the PKR gene among mammalian species. Individual differences in cognitive plasticity: an investigation of training curves in younger and older adults.

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The Brownian particle interacts with the solvent molecules through repulsive Lennard-Jones forces. Minimally invasive techniques for bypass surgery have played a large part of bringing this approach into contemporary practice. Dopant-Assisted Positive Photoionization Ion Mobility Spectrometry Coupled with Time-Resolved Thermal Desorption for On-Site Detection of Triacetone Triperoxide and Hexamethylene Trioxide Diamine in Complex Matrices. Differential EMG behavior was exhibited between the two no-expectancy groups, with the contingent group reliably lower in EMG activity than that noncontingent. Comparison of anterior and posterior vertebral column resection versus anterior release with posterior internal distraction for severe and rigid scoliosis.

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A retrospective chart review was conducted in 102 consecutive CKD patients receiving a CRT device for the treatment of advanced HF. The article described the experiences of elderly couples caring for each other using ethnographic methodology. The Mashona mole-rat, Cryptomys darlingi, lives in subterranean burrows that are completely sealed and is therefore rarely, if ever, exposed to light under natural conditions. Carbon and energetic uncoupling are associated with block of division at different stages of the cell cycle in several cdc mutants of Saccharomyces cerevisiae. In this review, we provide an overview of our work and discuss the next steps, focusing on the potential clinical implications of these findings.

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The granules acclimated quickly to the phenol loading, and stabilized only 1 week after phenol was introduced. Gender-dependent response in blood pressure changes following the inhibition of nitric oxide synthase. The non-linear kernel partial least squares (KPLS) model was used to separate the control and different radiation dose groups.

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A 50 years old patient underwent a polytrauma including an open fracture of the ankle. Microsomal nitro reduction is enhanced to a similar extent by haemoglobin, haemin and boiled haemoglobin, whereas myoglobin is about half as active. Substance P levels in plasma, pancreas, and lungs were found to be elevated in a caerulein dose-dependent manner.

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The whole body model successfully described temporal events in all tissues. Delivery of peptides and proteins through the blood-brain barrier. A long thoracic neuropathy was subsequently confirmed by electromyographic testing. Water soluble small-sized molecules mediate this process and a number of antagonists of these compounds have been found.

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Prolongation of skin allograft survival in mice following administration of ALLOTRAP. Quantitative 3D analysis of the canal network in cortical bone by micro-computed tomography. Infective agents causing severe course of the infectious process were found to have a high level of persistence properties.

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Bioprosthetic mitral reoperative mortality can be lowered by reoperations on an elective/urgent basis in low to medium NYHA functional class. Numerical atomic basis orbitals are variationally optimized for biological molecules such as proteins, polysaccharides, and deoxyribonucleic acid within a density functional theory. The authors tried to find relationship between parents with early onset myocardial infarction (AMI) and incidence of risk factors for ischemic heart disease in their children as compared to respective data for families with no incidence of myocardial infarction. Lower levels of urinary free cortisol were not related to medication use, sleep disturbance, or disability levels.

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We compared the management and outcomes of confirmed and suspected ectopic pregnancy 1 year before and one year after the transition from a nurse-led to a consultant-led early pregnancy unit in a London hospital. Organization and management of the surgical treatment of pulmonary tuberculosis In the present study, a dialytic method that uses a DNA aqueous solution to remove and enrich dioxins from polluted water was proposed. The expression of CYP17 in adrenocortical cells is stimulated by corticotropin (ACTH) via the signal transduction pathway involving cAMP and protein kinase A (PKA). As far as they are supported by data, recommendations for diagnosis and therapy are given.

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Alteration of immune function in women collegiate soccer players and college students. A functional PA subunit seems to be necessary to induce this negative effect, because an inactive point mutant was unable to decrease the steady-state levels or the half-lives of the reporter proteins. Five species were identified based on micro-morphological and molecular phylogenetic analyses. Intramolecular O-arylation of phenols with phenylboronic acids: application to the synthesis of macrocyclic metalloproteinase inhibitors.

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Isolated insular strokes and plasma MR-proANP levels on admission are independent predictors of NDAF and significantly improve the prediction accuracy of identifying patients with NDAF compared to known predictors including age, the NIHSS and lesion size. A critical analysis of the management protocols for idiopathic sudden sensori-neural hearing loss.