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Aprovel (Irbesartan)
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Irbesartan

The antagonism of the angiotensin receptor 1 receptors with Aprovel reduces the adipogenic activity of angiotensin II in obese Zucker rats, with the endpoint being reduction of the growth and differentiation of the adipocytes within the adipose tissue.

Other names for this medication:
Irbesartan, Avapro, Aprovel, Irovel,

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Aprovel is used to treat high blood pressure (hypertension) and to help protect the kidneys from damage due to diabetes. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Aprovel belongs to a class of drugs called angiotensin receptor blockers (ARBs). It works by relaxing blood vessels so that blood can flow more easily. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This drug may also be used to treat heart failure.

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The psychological troubles resulting of assault is difficult to estimating for a lot of GPs. In this study, we show that the conditional and/or ectopic expression of a nuclear receptor, hepatocyte nuclear factor 4alpha (HNF4alpha), triggers microvillus morphogenesis. We further determined that these targets are highly expressed on multiple cell types in MS and EAE lesions. Interaction between UbcM4 and UIP5 was observed in vivo and in vitro with bacterially expressed proteins. Bone marrow transplantation (BMT) represents an important therapeutic choice for several kinds of disorders: hematologic, metabolic and neoplastic pathologies can be treated with this strategy.

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In addition, these applications need special surface coating of the magnetic particles, which has to be not only non-toxic and biocompatible but also allow a targetable delivery with particle localization in a specific area. Clustering of the nine tasks by accuracy revealed different processing requirements in the participants with aphasia compared to the control group while clustering by reaction time revealed similar trends in both groups in that phonological (no-name) items required the most processing time. Aspartate aminotransferase (AST), alanine aminotransferase (ALT)

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The serine/threonine kinase PAK4 was identified first as an effector molecule for the Rho GTPase Cdc42. Caspase-9 and -8 cleave procaspase-3 to produce a p24 processing intermediate (composed of its prodomain and large subunit), which then undergoes autoproteolytic cleavage to remove the prodomain from the active protease. There is a paucity of published data available regarding psychiatric comorbid conditions in patients with epilepsy (PWEs) from developing countries. With a P value of less than 0.340 but greater than 0.320, RDS may or may not develop. Cancer bioassay data for HQ demonstrate limited effects and are not sufficient to classify HQ for human carcinogenicity.

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Novel treatment modalities for previously fatal diseases, including newer chemotherapeutic and biologic agents and the expansion of the indications for solid organ and stem cell transplantation, have resulted in prolonged patient survival and a significant increase in the population of immunocompromised hosts (ICHs). The recombinant plasmid pEGHsp65 was subsequently transfected into Hela cells, and the transfection rate was determined under confocal laser scanning fluorescence microscope at different times. Innate resistance to Schistosoma japonicum in a proportion of 129/J mice. Polyoxometalate clusters integrated into peptide chains and as inorganic amino acids: solution- and solid-phase approaches. The six sigma is a paradigm developed within the industrial domain for assessing quality and addressing goal and issues.

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There is a need for developing faster, reliable and reproducible methods for identifying the different strains of E. In this study, we describe a simple and sensitive high-performance liquid chromatography method with UV detection for determination of 1-(2-phenylethyl)-6-(quinaldin-4-yl) biuret (PEQB) in rat plasma. We describe 2 cases of oral carcinoma involving the mandible, treated with mandibular resection and reconstruction.

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Targeting Nicotinamide Phosphoribosyltransferase as a Potential Therapeutic Strategy to Restore Adult Neurogenesis. In the present study, we evaluated the overall effects of a 2-week daily consumption of strawberries on plasma antioxidant status, membrane lipid susceptibility to ex vivo-induced oxidation, and erythrocyte and mononuclear cell resistance to oxidative damage in apparently healthy volunteers. Correlation between magnetic resonance imaging and radiographic measurement of cervical spine in cervical myelopathic patients. Replantation of distal thumb amputations is difficult because of the anatomic orientation of the thumb and the location and size of vessels. The leukocyte count was found to drop, and the erythrocyte one -- to rise.

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Microdialysis of histamine in the skin of patients with mastocytosis. Coexistence of trichostasis spinulosa and eruptive vellus hair cysts.

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Caffeine, theobromine and xanthine have a quenching effect on the production of hydroxyl radicals, as well as on oxidative DNA breakage by hydroxyl radicals. Also, the washout of radioactivity from tissue was slower, and the dose of radiation exposure was estimated to be higher, with TW-80 than with HSA. We present the case of a 25-year-old woman suffering from chronic severe headaches and syncope associated with an expanding cyst of the septum pellucidum. Molecular modeling study on the dynamical structural features of human smoothened receptor and binding mechanism of antagonist LY2940680 by metadynamics simulation and free energy calculation.

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CXR revealed a left pan-hemi-thoracic opacity whilst better definition using CT-pulmonary angiography (CTPA) indicated an acute tension gastrothorax secondary to a large left-sided diaphragmatic hernia. Of particular relevance in this context is its modulation of glutamate release. Obstetrical management and possible perinatal complications are discussed. Samples from 20 healthy volunteers were collected by nasal lavage.

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Despite encouraging experimental and clinical data obtained so far may suggest a potential future indication in this population, routine use of therapeutic hypothermia in acute myocardial infarction patients needs further investigation and it is not currently recommended. The child had a positive skin prick test reaction to pectin and a high RAST reaction to cashew and pistachio. The results obtained indicate the prevalence of high molecular weight PAHs in all the samples. Approaches for the generation of new anti-cytomegalovirus agents: identification of protein-protein interaction inhibitors and compounds against the HCMV IE2 protein.

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To assess the role of superoxide dismutase in protecting Escherichia coli from killing by human serum and neutrophils, we constructed isogenic, smooth-lipopolysaccharide K-12 strains, either sod wild-type, delta sodA, or delta sodA delta sodB. The sounds of silence: sexuality information for cancer patients. Effects of Roux-en-Y gastric bypass on energy and glucose homeostasis are preserved in two mouse models of functional glucagon-like peptide-1 deficiency. Although conceptual/methodological heterogeneity and lack of replication are key limitations of studies in this area, findings speak for a prominent role of cognitive disinhibition, delay discounting and impulsive decision-making in the ability to successfully achieve and maintain abstinence during and following addiction treatment. Ciliary block glaucoma: malignant glaucoma in the absence of a history of surgery and of miotic therapy.

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Our data indicate that the nucleoid-associated protein IHF is one such protein. As a first step in this process, we produced a plasmid DNA vaccine that includes the gene encoding the P. The amino acid to nucleotide contacts provided distance constraints that enabled us to build a three-dimensional model of the protein-DNA complex.

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The impact of stuttering on employment opportunities and job performance. Eighty-eight sexually active women in heterosexual romantic relationships completed surveys assessing evaluative, affective, and behavioral body image and sexual functioning. mariana, primer pairs for all six polymorphic SSR loci successfully amplified specific fragments from genomic DNA and resolved polymorphic microsatellites of comparable sizes in P.

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Familial mediterranean fever (FMF) is an hereditary disease transmitted in an autosomal recessive way and characterized by recurrent and brief episodes of fever and pain secondary to serositis. The theory is shown to be in good agreement with the simulation. Haematuria is not a risk factor of hypertension or renal impairment in patients with haemophilia. This paper looks at the current definition, diagnostic methods and management of AIN. It is suggested that the inhibitory effects of morphine may be mediated by the kappa receptor.

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Long-chain n-3 polyunsaturated fatty acid dietary recommendations are moderately efficient in optimizing their status in healthy middle-aged subjects with low fish consumption: a cross-over study. AVC is progressive, appearing de novo with progressive atherosclerosis whereas established AVC progresses independently of atherosclerotic risk factors and faster with increasing initial AVC loads. Largely overlapping neural circuits control these systems, and this anatomical arrangement optimizes opportunities for mutual influence.

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They share a high degree of sequence similarity, particularly in the cytoplasmic domains involved in intracellular signaling. In patients with chlorpromazine-induced hyperprolactinaemia and galactorrhoea, pyridoxine did not reduce the elevated levels. It was concluded tht some of the EEG abnormalities are acquired, and apparently produced by a metabolic disturbance caused by diabetes.

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Developing consensus on hospital prescribing indicators of potential harm for infants and children. We demonstrate now that CD27(low) IFN-gamma-producing CD4 T lymphocytes accumulate in the lungs but are rare in LNs. Only selected wavelengths from this range have previously been accessible, by Raman shifting of the second, third, and fourth harmonics of the Nd:YAG fundamental in hydrogen. As immunological cross-reactions due to NTM hamper the diagnosis of bovine tuberculosis, the precise identification of NTM strains would be essential in the veterinary diagnostics, especially for potentially zoonotic strains.

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Sir3p self-associates extensively in moderate salt and at micromolar protein concentrations producing a broad range of oligomers that sediment from 8 to in excess of 85 S. The bioassay was successfully applied to the determination of paclitaxel in human plasma. Subsequently, these modified amino acids were used in solid phase peptide synthesis (SPPS), and their potential utility in an extracellular matrix metalloprotease (MMP-1) activity measurement via FRET and/or quenching studies was demonstrated.

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Originally only DHEA or DHEAS have been considered to be responsible for all of the effects. Further work is in progress using different recombinases and other promoters to optimize recombinase expression as well as to test these genetic constructs in contaminated environmental samples such as soil and water. Below the critical interpillar spacing, however, the pillars always inhibit the nucleation, and the wetting state of the critical nucleus depends on the pillar height. It is believed that lack of this pigment in periodontal tissues might influence periodontal disease progression. The likelihood of recurrent Complex Regional Pain Syndrome (CRPS), residual and phantom limb pain and persistent disability after amputation is poorly described in the literature.

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All the fractions obtained were profiled with regard to their major polyphenolic constituents, using liquid chromatography-diode array-mass spectrometry. These results suggest that transient exogenous Bcl-2 expression at the early stage of the disease protects against motor neuronal degeneration in G93A mice by retarding translocation of cytochrome c into the cytosol, and regulating caspase-1 for a substantial period. Preferably exercise training should be started during the predialysis stage, however, it is equally effective in dialysis patients and after renal transplantation. Utilization of a post-anammox PACL chemical dosing stage can achieve the objective of precipitating any residual DON and NRDP and producing an effluent that has lower dissolved nutrients than the pre-digestion KWTF dewatering centrate scenario. Intracranial administration of metyrapone, a blocker of the enzyme 11-beta-hydroxylase, which is essential for the biosynthesis of corticosteroids, resulted in profound stimulation of the nucleus preopticus and the CRF-ACTH axis in the teleost, Clarias batrachus.

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The centrosomal binding domain of DdCP224 resides within the C-terminal fifth of the protein. The promotion of staff nurses as educational resources has a positive effect on their participation in a wound and skin care team. The analysis of FVIII inhibitors is confounded by polyclonality and the size of FVIII. Association of maternal endothelial dysfunction with preeclampsia. The present study reports values of colony forming units (CFU) of total anaerobic bacteria, Actinobacillus actynomicetemcomitans (Aa) and Porphyromonas gingivalis (Pg) from the subgingival plaque from a child with PP, collected immediately before and 1 year after extractions of the primary teeth affected with ABL.

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PSC collection during early hematopoietic recovery from intensive chemotherapy allowed the collection of diploid-rich stem cells, mostly in chronic-phase CML. An ancillary finding was that the incidence of attention deficit/hyperactivity disorder was significantly higher in children with NVLD (with and without APD) than in the general population.

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Dorsoventral patterning of the embryonic neural tube gives rise to multiple progenitor cell domains that go on to differentiate unique classes of neurons and glia. Based upon its deduced amino-acid sequence, the product of the P. Retrospective serial case reports of patients who underwent routine clinical examination and OCTA of the posterior pole using both a DRI OCT Atlantis prototype and Triton Swept-Source OCT. Replication of human influenza A/H3N2 and A/H1N1 viruses was studied in human CACO-2 cells, a continuous line of intestinal epithelial differentiated cells.

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Except for two missense substitutions, all are expected to cause a premature termination of the FANCA protein at various sites throughout the molecule. Creatine kinase isoenzymes BB in the serum of renal-disease patients, distinct from an albuminlike artifact.

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Calculated attributable risks showed that most child cancers and leukaemias are probably initiated by such exposures. Explicit associative memory relies on different neural substrates depending on similarity of the items associated.

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PSD-95 and PKC converge in regulating NMDA receptor trafficking and gating. Elevated white blood cell count and carotid plaque thickness : the northern manhattan stroke study. Anesthetic-induced burst suppression EEG activity requires glutamate-mediated excitatory synaptic transmission.

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When the manipulation reached brainstem and the instrument touched the left vagus nerve, evoked potentials appeared on bilateral electrodes. Attachment affected expression of at least 454 different genes, with 163 being upregulated and 291 being downregulated. By 6 to 12 months, the scotomata had disappeared despite large areas of retinal pigment epithelial hyperpigmentation remaining. Mapping the interaction of bradykinin 1-5 with the exodomain of human protease activated receptor 4. We report the case of a patient who after a minor fall developed a subdural hematoma requiring craniotomy that likely was precipitated by concomitant use of high-dose omega-3 fatty acids 6 g/day with both aspirin and warfarin.

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In addition, karyotypes and morphological properties of these strains were evaluated. Herein, we demonstrated that treatment of TSA resulted in a significant decrease of the viability of H157 cells in a dose-dependent manner, which was revealed as apoptosis accompanying with nuclear fragmentation and an increase in sub-G0/G1 fraction. Individual exposure-effect relationships may be predicted by this model, due to the adaptability to a specific subject.

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Severe diabetic retinal disease and dementia risk in type 2 diabetes. Mechanisms mediating reproductive allochrony can influence population divergence and the capacity of populations to respond to environmental change. Age-related changes in the cardiomyocyte population of the heart ventricles of white rats

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Previous studies on the effects of work factors on absence and disability retirement have only addressed a limited set of factors and little is known about the mechanisms that govern relationships between work exposures and sickness absence/disability retirement. Role of chemotherapy prior to orchiectomy in metastatic testicular cancer-is testis really a sanctuary site? Pulmonary involvements observed in lupus erythematosus disseminatus. Given that the elevated serum semicarbazide-sensitive amine oxidase (SSAO) activity is associated with the severity of carotid atherosclerosis in clinic, the current study aims to investigate whether SSAO inactivation by semicarbazide is beneficial for established atherosclerotic lesions in LDLr knockout mice on a high-fat/high- cholesterol Western-type diet or after dietary lipid lowering. Protein kinase in HeLA nucleosomes: a reevaluation of the interactions of histomes with the ends of core particle DNA.

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Combining electroencephalographic activity and instantaneous heart rate for assessing brain-heart dynamics during visual emotional elicitation in healthy subjects. A kinetic model similar to that of phytochrome action explained quantitatively the fluence rate-response curves of the fragmentation. In monkeys treated with a combination of LHRHa and radiation, FSH started rising soon after the LHRHa-loaded minipump was removed (after the end of radiation).

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DNA polymerase A is most active with activated DNA, but will also use native DNA and synthetic RNA and DNA templates with DNA primers. In this study, the in vivo production, fate and pathogenicity of cell-specific MP during Plasmodium berghei infection of mice were evaluated. Biliary spasmolytic action of 3-(2,4,5-triethoxybenzoyl)propionic acid (AA-149) in dogs. Newborn screening for galactosemia and other galactose metabolic defects.

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Sonication for 30 s led to smaller differences in the mean globule size. The objective of this review is to summarize the current knowledge of the molecular mechanisms underlying phagosomal maturation and its subversion by parasitic microorganisms.

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phenylpyruvica has never been reported in the dog, but sporadic cases are reported in humans. Life history of the coccidian parasite, Eimeria arloingi, in domestic sheep. Desoxycholic acid increased the bacteriostatic activity of gentamicin and neomycin by 781.3 and 2083.3 times respectively and cholic acid increased it by 382.7 and 2083.3 times. Attitudes and practices of breast cancer consultations regarding sexual issues: a nationwide survey of Japanese surgeons.

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The antibody 20F10-catalyzed reaction was studied in detail, exploring its selectivity, substituent effects, substrate and hapten binding, kinetic parameters and irradiation wavelength dependence. AIDS: sonography of hyperechoic renal pyramids in renal candidiasis. It is known that some proteins required for mismatch repair bind to mismatched base pairs prior to carrying out repair. A quantitative metrology for performance characterization of five breast tomosynthesis systems based on an anthropomorphic phantom.

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This spatial distribution of voltage suggested that this language-sensitive field potential was generated in the neocortex near the collateral sulcus and anterior fusiform gyrus. Some specimens mopral 10 mg posologie d'ortie were pretreated by silver staining for selective visualization of acidic proteins of the nucleolar organizer regions.

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The aims of mechanical ventilation are to correct hypoventilation, improve oxygenation and oxygen transport and reduce the work of breathing. The unusually ambien generic manufacturers of alprazolam long TM6 plays an important role on the binding behavior of the antagonist in the pocket of SMO receptor. Cleavage of the A-ring in the starting reaction indicates that an alternative pathway must be operating, instead of the general oxidative one. After 4-8 weeks, TUNEL- and Fas-positive cells were observed in the media, denoting progressive apoptosis. The scopolamine model of amnesia has been used to test the pharmacodynamic efficacy of oxiracetam in 12 healthy volunteers.

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By this means melatonin attenuates transendothelial cell migration and edema, which contribute to tissue damage. The clinic is unspecific and the treatment, medical and expectant. Responses were initially fitted over a concentration range of rosuvastatin dose equivalent atorvastatina 15.625 to 500 microM using a model which incorporated terms for a saturable binding site. Cost analysis of procedural fee for percutaneous transluminal coronary angioplasty at six Japanese hospitals Whereas the detection profile of the kits is fixed at a general specificity level, the design of primers can be adjusted to differentiate between highly specific strains.

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In the present study, we aimed to determine whether the use of self-retaining barbed sutures (SRBS) instead of conventional sutures during open partial nephrectomy leads to improved surgical outcomes. Embryologic origin of the various epithelial cell cuvarlix orlistat 120 mg cheap types in the second kind of thyroid follicle in the C3H mouse.

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Important pharmacokinetic differences among the agents (e.g., route of elimination) allow for selection of an appropriate agent based on individual factors such as cost and tolerability. The results of this study will be disseminated through relevant, peer-reviewed journals and international conference presentations. Asthma-like symptoms assessed by the IUATLD questionnaire have good validity, both for specificity and sensitivity, for asthma patients recruited in chest clinics. The antibodies cross-reacted with 3 shark CNS polypeptides apart from the original antigen, with 2 major natrium diclofenac gel over the counter polypeptides from shark peripheral nervous system myelin, with the Po protein from chicken and sheep peripheral nervous system myelin, but with none of the components of bovine CNS myelin. In vitro binding of 3H-nimodipine to human brain membranes is demonstrated in this study.

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Endogenous as well as exogenous HGF attenuated the progression of the fibrosis caused by obstructive nephropathy in these aldactone 50 mg nebenwirkungen diclofenac mice. To assess the effectiveness of oral melatonin taken in different dosage regimens for alleviating jet-lag after air travel across several time zones. Recently, increasing evidence has suggested that microRNAs (miRNAs) are involved in drug resistance. Beyond angiogenesis: the cardioprotective potential of fibroblast growth factor-2. Population-based interventions engaging communities of color in healthy eating and active living: a review.

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Prostaglandin I(2) and E(2) mediate the protective effects of cyclooxygenase-2 in a mouse model of immune-mediated liver injury. There was no correlation between the joint angle and the static response. She had a history of iron-deficiency anemia due to long-standing celiac disease that was managed with a gluten-free diet. protica protein ketchup restaurant By contrast, experience of palliative care was explained in radically different terms, with a clear shift in the nature of the interaction and resulting care, to bring effective communication and relief from suffering. administered NMDA (5 mg/kg) or kainate (2.5 mg/kg) elevated the ACTH and CS levels already at 5 min in control (sham-operated Wistar or heterozygous Brattleboro) rats.

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Modification of a High-Throughput Automatic Microbial Cell Enumeration System for Shipboard Analyses. Severity of illness scoring systems are widely used in critically ribavirin and interferon manufacturer ill patients. Randomized crossover trial comparing the eZ.on plastic condom and a latex condom. This condition thus has to be considered in the differential diagnosis of primary intramedullary tumours, or metastatic disease with involvement of the spinal cord. Between January 2009 to December 2010, a total of 3,758 women aged 40-69 years were recruited in this prospective study.