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In addition, AP extract reduced IL-6 mRNA expression in the medulla and mesencephalon and also mRNA levels of TNFalpha in the mesencephalic region. The enzyme hyaluronidase, its biological, pathogenetic, and clinical significance Biopsies from leg ulcers of 21 patients and from normal skin of nine healthy volunteers were examined immunohistochemically for selected growth factors and cytokines. Racial and ethnic differentials in overweight and obesity among 3-year-old children.

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Viruses strongly influence the ecology and evolution of their eukaryotic hosts in the marine environment, but little is known about their diversity and distribution. Virtual Expert Mass Spectrometrist (VEMS) v3.0 includes an algorithm for extracting monoisotopic single-charged peaks and their corresponding retention time from liquid chromatography (LC)-MS data. A diet rich in apple antioxidants might exert a beneficial effect in the prevention of gastric diseases related to generation of reactive oxygen species.

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To evaluate different diagnostic methods and criteria concerning the classification of reproductive stages, we examined 20 testicular samples obtained at necropsy in psittacine birds of different species and testicular biopsy samples collected from 9 cockatiels (Nymphicus hollandicus) and 7 rose-ringed parakeets (Psittacula krameri) by endoscopy 4 times over a 12-month period. The main thrust of this paper is to propose that tumorigenesis should be studied in terms of cellular-population kinetics in response to a biological challenge rather than according to chemical or energetic parameters of that challenge.

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Detection of cancer stem cells (CSCs) in ovarian cancer, influence of CSCs on overall survival, disease free interval. In the present study, Southern hybridization, together with amplification by PCR and DNA sequencing techniques, was used to examine the regions homologous to chloroplast rps19 in the mitochondrial genomes of several gramineous plants. To examine if severity grading performed by patients with hand eczema using a self-administered photographic guide was in agreement with the assessment performed by a trained dermatologist.

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High available P grains or phytase enzyme supplementation can reduce total and soluble P in animal manures by reducing the need for diet supplementation with inorganic P. A narrative review is undertaken based on traditional and contemporary literature for yoga, along with scientific articles available on yoga and exercise including head-to-head comparative trials with healthy volunteers and patients with various disease conditions.

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Assessing the impact of VOC-contaminated groundwater on surface water at the city scale. Increase of neutrophil adhesion and vasoconstriction with platelet deposition after deep arterial injury by angioplasty. The comparison with the graft loads under various conditions provided the following conclusions: Unlimited passive motion of the knee joint can be done without risk.

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The revised Personal Lifestyle Questionnaire for early adolescents. Interestingly, histologic examination of the pulmonary metastasis revealed so-called xanthogranuloma. Research progress of the side effect and application prospects of CAR-T cells in the treatment of malignant tumors

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The analysis of the colored pottery figurines from Yangling Tombs of Han Dynasty was realized by X-ray diffraction, emission spectrum, infrared spectrum, X-ray fluorescence and fiber optics reflectance spectroscopy(FORS). Fibrin glue alone (whether negatively- or positively-charged) does not have the tensile strength to maintain an anastomosis without sutures. The structure of mycoplanecin A was determined by the analysis of chemical degradation products and by mass and 1H and 13C NMR spectrometries. Conditions are summarized for manipulating and stabilizing fluid objects based on the acoustic radiation pressure of standing waves.

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In estrous estrogen-primed female rabbits with electrodes chronically implanted in various subcortical regions of the brain, the intraventricular injection of an ovulation-inducing dose of norepinephrine (NE) stimulated a prolonged episode of high amplitude 40-60 cps electroencephalographic (EEG) activity in the olfactory bulb (OB) and its projections. The father of the proband exhibited cerebellar signs and pigmentary retinopathy. Flurazepam has been shown to be the drug of choice for purely symptomatic insomnia. Whereas IL-7R(-/-) thymocytes are arrested at the double-negative stage, IL-4R, IL-9R, or PRLR all imparted some progression to the double-positive stage. In an experimental task, parents and toddlers played together with multiple toys.

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Rapid and highly sensitive electrochemical determination of alkaline phosphatase using a composite tyrosinase biosensor. A series of 1-substituted 1,2,3,4-tetrahydro- and 3,4-dihydro-beta-carboline derivatives have been synthesized and evaluated for antitumor activity against murine P-388 and human tumor cell lines, KB-16, A-549 and HT-29.

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The antigens used for antibody assay were poly(ADP-ribose), left-handed Z-DNA, double-stranded DNA (dsDNA), single-stranded DNA (ssDNA), and calf thymus histones. We propose that pim1 is required for the reestablishment of nuclear structure following mitosis in fission yeast.

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In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via enzymatically degradable amide bonds, each contributing to a different anti-tumour mechanism of action of the polymer-doxorubicin conjugate. Microwave-enhanced transition metal-catalyzed reactions allow easy introduction of a variety of substituents at the C3 position.

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The lacrimal system was intubated through the upper lacrimal canaliculus with a silicone drainage system for 6 weeks. 34,893 persons first hospitalized for firearm injuries at the King/Drew Medical Center in Los Angeles from January 1978 through December 1992. Kinetics of selected plasma cytokines during innate-adaptive immune response transition in adult cattle infected with the bovine ephemeral fever virus.

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Diosgenin, a steroidal saponin from plants, exhibits many biological potentials. Conditional nuclear localization of hMLH3 suggests a minor activity in mismatch repair and supports its role as a low-risk gene in HNPCC. Three new drimane-type sesquiterpenoids chaetothyrins A-C (1-3), were isolated from an endolichenic fungus Chaetothyriales sp. Postoperative statistical analysis revealed a difference between the two groups, such that non-smoking patients had a better outcome. MK-801 likewise improved the water maze performance of the ischemically-impaired mice, but to a lesser extent.

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These results prove that trace and ultra trace element concentrations in plasma are changeable by nutritional conditions, and suggest that new physiological functions may be found for these elements, and that they may be proved to be essential for mammals. Children who have needed neonatal intensive care (NIC) are considered to be at risk for deficits such as developmental co-ordination disorder and attention-deficit/hyperactivity disorder. The preclinical (Years 1 and 2) curriculum was evaluated by reviewing all syllabi and other printed materials for the presence and quantity of instruction in the specific clinical preventive medicine topics. During repeated training in 3 days after amnesia induction, the skill was formed more rapidly than during the initial training.

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Mefloquine is an important antimalarial drug for treatment and prophylaxis of chloroquine-resistant malaria. A three-stage gene-environment investigation was conducted for NAT1, NAT2, and GSTP1 variants. Moreover, as happens with CsA due to the inhibition of NFATc1, Interleukine-2 (IL-2) released to the culture medium was significantly decreased with all Spongionella compounds. The inability of the eye to transport extravascular protein across the abnormal sclera is probably the cause of prolonged exudative detachment of the uvea and retina in these patients. The aim of this study was to find out whether MTX treatment induces different histological response patterns in these two diseases.

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In the present study, we present the first evidence of a protein kinase identified in rat cerebral cortex/hippocampus that is activated by InsP(6). Evaluation of a preoperative multimedia information program in surgical oncology. Polymethylmethacrylate (hard) contact lens-wearing Navy divers involved in hyperbaric research complained of ocular discomfort, halos, specular highlights, and decreased visual acuity during and immediately after the decompression phase of dry chamber dives. It is suitable for identifying a large number of samples obtained from epidemiological studies and hence, reducing the death rate of rotavirus-infected patients.

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Growth kinetics and short-term outcomes of cT1b and cT2 renal masses under active surveillance. The development and validation of an Arab- and Chaldean-American name database will enhance research efforts in this population subgroup. The present dynamic blade system provides significant improvements in CNR for the same imaging dose and localization of imaging dose to a predefined volume of interest. Neither LPS nor SEB modulated the p55TNFR gene expression in any region or cell type of the brain, and LPS but not SEB induced p75TNFR mRNA in the CVOs.

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The inhibition of RRR-alpha-tocopherol of protein kinase C is not the consequence of a direct interaction but is due to a diminution, produced by RRR-alpha-tocopherol of the kinase phosphorylation. If found to be effective it has the potential to provide individualised support to people with diabetes across New Zealand (and internationally), thus extending care outside the clinic environment.

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Oxidative stress is a leading cause of various diseases, including ischemia and inflammation. Even when adjustment is made for potential confounding, interpretation of adjusted estimates must still consider the potential for residual bias. The structure of tumor tissue obtained from FS-1-transplanted nude mice is very much like the original tissue of SCC. An improvement based on the determination of plasma clot retraction, performed in a plasma with a standard count of platelets (100,000/mm3) is presented.

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Providing health care for homeless or low-income families presents many challenges and rewards. While the Messel forest web, with 630 taxa, displays differences compared to extant webs, they appear to result from high diversity and resolution of insect-plant interactions, rather than substantive differences in structure. To explore the clinical value of computer-assisted surgical planning in the treatment of ankle fractures.

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Here, we identified distinct roles of entorhinal cortex and ventral midline thalamus for the functional development of prefrontal-hippocampal interactions. Previous arsenic treatment and x-ray irradiation seemed to have a similar effect. The plants were, chamomile (Anthemis nobilis L.), cinnamon (Cinnamomum verum J. A pilot clinical trial of vaccination with dendritic cells pulsed with autologous tumor cells derived from malignant pleural effusion in patients with late-stage lung carcinoma. Our data indicate that endothelin-1 is critical in the development of cerebrovascular and cognitive impairments with experimental cerebral malaria.

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The study was performed within the Rotterdam Study, a population based cohort study. Removal of the small non-functioning upper renal segment was not necessary in most instances.

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The role of UV light in the pathogenesis of digital papular calcific elastosis. A total of 152 patients (176 eyes) with peripheral retinal breaks were assessed, among them 57 men and 95 women, aged from 18 to 76. Characterization of the microbial conversion products of auramycinone by Streptomyces coeruleorubidus ATCC 31276. Activation of HH pathway promoted cell survival, growth, and invasion partially through HGF and MET signaling. On-going collaborative environmental investigations are described.

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