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Acivir (Acyclovir)

Acivir is an antiviral drug, a synthetic nucleoside analogue, that has inhibitory activity (interferes with viral replication) against the herpes viruses, including herpes simplex 1 and 2 (cold sores and genital herpes), varicella-zoster (shingles and chickenpox), and Epstein-Barr virus (mononucleosis). Viruses take over living cells and reproduce themselves, often at the expense of the host cell. The Acivir is converted to an active form by the virus itself, and the virus then uses the active form of Acivir rather than the nucleoside it normally uses to manufacture DNA, a critical component of viral replication. Incorporation of active Acivir into new viral DNA stops the production of the DNA. Virally infected cells absorb more Acivir than normal cells and convert more of it to the active form, which prolongs its antiviral activity. The FDA approved Acivir in March 1982.

Other names for this medication:
Acyclovir, Abduce, Acic, Aciclobeta, Aciclomed, Aciclostad, Aciclovirum, Acifar, Acihexal, Aciklovir, Acitop, Acivir, Acivirex, Acivision, Acix, Actios, Activir, Acycloguanosine, Acyl, Acyrax, Acyvir, Aklovir, Antivir, Asiviral, Avir, Aviral, Avix, Avorax, Blistex, Cicloferon, Cicloviral, Clinovir, Clirbest, Clopes, Clovate, Clovir, Cusiviral, Cyclomed, Cyclovax, Cyclovex, Cyclovir, Danovir, Declovir, Epsin, Eurovir, Hascovir, Hernovir, Herperax, Herpesil, Herpesin, Herpex, Herpin, Herplex, Heviran, Immunovir, Lisovyr, Lovir, Lovire, Lovrak, Medovir, Menova, Ocuvir, Poviral, Ranvir, Remex, Rexan, Scanovir, Sitavig, Sophivir, Soviclor, Supraviran, Telviran, Uniplex, Vilerm, Viraban, Viralex, Viratac, Viratop, Virest, Virestat, Virex, Virless, Viroclear, Virolex, Viromed, Virosil, Virostatic, Virovir, Virucid, Viruderm, Virustat, Virux, Vivorax, Xiclovir, Xorox, Zevin, Ziverone, Zoral, Zorax, Zoraxin, Zovirax,

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Ophthalmic Acivir comes as an eye ointment to apply to the eyes. It is usually applied five times a day (about every 3 hours while awake) until the eye heals, and then 3 times a day for another 7 days. Apply Acivir eye ointment at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Acivir eye ointment exactly as directed. Your doctor will tell you when you can start using ophthalmic Acivir 3 times a day. Do not use more or less of it, or use it more often than prescribed by your doctor.

You should expect your symptoms to improve during your treatment. Call your doctor if your symptoms get worse or do not go away, or if you develop other problems with your eyes during your treatment.

To use the eye ointment, follow these instructions:

  1. Wash your hands thoroughly with soap and water.
  2. Use a mirror or have someone else apply the ointment.
  3. Avoid touching the tip of the tube against your eye or anything else. The ointment must be kept clean.
  4. Tilt your head forward slightly.
  5. Holding the tube between your thumb and index finger, place the tube as near as possible to your eyelid without touching it.
  6. Brace the remaining fingers of that hand against your cheek or nose.
  7. With the index finger of your other hand, pull the lower lid of your eye down to form a pocket.
  8. Place a 1 cm (about a 1/2 inch) strip of ointment into the pocket made by the lower lid and the eye.
  9. Gently close your eyes and keep them closed for 1 to 2 minutes to allow the medication to be absorbed.
  10. Replace and tighten the cap right away.
  11. Wipe off any excess ointment from your eyelids and lashes with a clean tissue. Wash your hands again.

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A theory is developed to explain this deviation from ideal second-order kinetics. Non steroidal anti-inflammatory drug-based pain control for minimally invasive direct coronary artery bypass surgery. The aims of this study were to examine the morbidity and mortality associated with extended resection and also to determine the survival benefit.

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The obstacles reflect the real world that palliative care professionals must negotiate each day, giving rise to a form of care that was good enough. For a prostate case, improved bladder sparing was achieved through the use of the new algorithm. Of the eight patients for whom the result was a functioning prosthesis, two had significant restriction of motion and one had moderate pain. The relationship of glucose tolerance to sleep disorders and daytime sleepiness. Colposcopic impressions of acetowhitening or worse are highly sensitive for identifying cervical precancers and reproducible on static image-based pattern recognition.

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Although our understanding of the structure and functioning of the synthase has made enormous progress in recent years, our understanding of regulatory mechanisms is still rather preliminary. However, the mechanism by which the methylation status of the repaired cytosines is restored has remained unknown. The optimal use of cisplatin as a chemotherapeutic drug has been limited by its nephrotoxicity. Since the early 1970s, researchers have expressed concern about the emotional well-being of family members after traumatic brain injury (TBI), and it is now widely acknowledged that TBI has long-term effects on the patient and relatives alike. The effect of subtotal masking on wave V latency was reduced for both tone-burst frequencies when the response-generating region of the cochlear partition was limited by high-pass maskers.

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Suspected osteopathology in chronically ill children often necessitates the assessment of bone mineral density. Autophagy-targeted vaccine of LC3-LpqH DNA and its protective immunity in a murine model of tuberculosis. For several years, efforts have been made to rectify the artifact problems arising from the use of glass fiber filters with this sampler.

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In the gaps between the subendothelial SM and endothelium there are particles of elastin which form the structure resembling an additional elastic membrane. This study used a phased and user-centered approach to develop a pain management algorithm for adolescents with cancer and the system requirements of an associated app.

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However, objects often are composed of several parts, and parts are central to theories of object recognition. The influence of applied pressure on the fouling mechanism during bovine serum albumin (BSA) dead-end microfiltration (MF) has been investigated for a polyethersulfone acidic negatively charged membrane (ICE-450) from Pall Co. We found a total of 22 studies in both animals and humans hinting of evidence that placebos may work as a sort of dose extender of active painkillers.

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Information on each of these criteria was sought for every assessment conducted in Ireland up to July 2015. Many methods have been proposed for RNA secondary structure comparison, and new ones are still being developed. Via 3D numerical simulations and a model of the two-phase flow we predict the location of particle accumulation, which is in excellent agreement with experimental data. Therefore drugs that modify the composition of lipid rafts might influence the efficacy of cellular signal transduction.

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When it corresponded to all above, it was defined to SHS, and it classified as MCS (multiple chemical sensitivities) without above conditions. Web-based apps for reflection: a longitudinal study with hospital staff. Because such recurrences cannot be cured, better adjuvant chemotherapies are urgently required. Ki67 Frequency in Breast Cancers without Axillary Lymph Node Involvement and its Relation with Disease-free Survival.

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Catalyzed cis-trans isomerization of retinals by crude tissue extracts. We previously demonstrated that exposure of CCL39 lung fibroblast cells to alpha-thrombin inhibits interleukin-6 (IL-6)-induced tyrosine phosphorylation of Stat3 (signal transducers and activators of transcription-3) protein via a mitogen-activated protein (MAP)-kinase dependent mechanism. Related literature on brain abscess with special emphasis on intraventricular rupture is reviewed.

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Because the quantity of endothelial progenitor cells (EPCs) in the peripheral blood is correlated inversely with cardiovascular risk, we studied whether such abnormalities could also be observed in patients with RA. The insertion site of the right pulmonary veins was detected in every patient and in ten patients has been verified at operation. Candidates should have medically intractable, disabling epilepsy.

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Because these solo hoots are almost always given out of view of females, they may be dishonest signals of male mating attempts. For RICS, a set of microscopy images is obtained by single-photon confocal laser scanning microscopy (CLSM). The derived theoretical expressions could find application for interpretation of experimental data on production and stability of Pickering emulsions. A 33-year-old white man with cystic fibrosis and severe chronic pulmonary disease developed nephrotic syndrome and was found to have secondary systemic amyloidosis. Correction: Exome Sequencing of Index Patients with Retinal Dystrophies as a Tool for Molecular Diagnosis.

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Immunohistochemical expression of insulin-like growth factor binding protein-3 in invasive breast cancers and ductal carcinoma in situ: implications for clinicopathology and patient outcome. Efficacy of sildenafil as treatment for idiopathic pulmonary arterial hypertension may be extended to patients with Eisenmenger syndrome. However, gastroparesis is common, and jejunal placement with gastric decompression leads to delays in feeding. This study aims to develop and evaluate a combination of isothermal nucleic acid amplification and simple lateral flow dipstick detection of the malaria parasite for point-of-care testing.

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