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To determine the effect(s) on glucose control, insulin dose, and circulating insulin levels of the addition of a sulfonylurea (Glipizide) to the treatment regimen of patients with insulin-requiring type 2 diabetes mellitus. Glipizide causes a more pronounced and sustained postmeal insulin secretory response compared with nateglinide.

Other names for this medication:
Glipizide, Actine, Dipazide, Gabaz, Glibenese, Glide, Glidiab, Glipizida, Glucotrol, Glynase, Melizide, Mindiab, Minodiab, Ozidia, Sucrazide,

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Glipizide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glipizide is in a class of medications called sulfonylureas. Glipizide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Glipizide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

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Analyses of expression and localization of two mammalian-type transglutaminases in Physarum polycephalum, an acellular slime mold. An algorithm to extract the 3D morphology from a neuron is presented. Covering of skin defects of the hand by a free skin-adipose tissue flap with microvascular anastomosis The effects of CH-11 were associated with activation of caspase-8, -9, and -3, cleavage of poly(ADP-ribose)polymerase-PARP, and decreased mitochondrial membrane potential (MMP), but these parameters were not significantly changed after PUFA pretreatment.

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After 3 months short vessel sprouts were seen, but regeneration was mostly incomplete. Treatment of chronic rhinosinusitis with intranasal amphotericin B: a randomized, placebo-controlled, double-blind pilot trial. Automating this task could yield more accurate blood pressure readings. The proportion of androgynous and undifferentiated individuals was much greater among self-labeled homosexual women. The regioselectivity of the addition is explained by reversal of polarization of the azadiene due to the electron-withdrawing character of the halogenated phenyl substituents.

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This side effect can be compensated by a single switch, if the sample contans N2O. The neurologist confirmed final diagnoses after a median follow-up interval of 4.8 years. The different clinical stages of the lesions from onset to resolution and the possible etiologic factors are described in detail, as well as a discussion of the differential diagnoses of palatal ulcers. Positive benefit of postnatal treatment in congenital toxoplasmosis.

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Postmortem analysis of hearts yielded significant correlation between in vivo radiotracer accumulation and ex vivo gamma-counting. Using the rBM system we have successfully grown primary bone marrow cells from normal donors and patients with amyloidosis, and various hematological malignancies.

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Articles suggesting the zoonotic potential of certain human diseases (eg, multiple sclerosis, rheumatoid arthritis, and leukemia) periodically appear in the literature and frequently receive considerable attention in the popular press. To investigate the expression of protein kinase C alpha (PKC alpha) in inflammatory cells and the level of interleukin-5 (IL-5) in induced sputum in asthma patients and the effect of inhaled glucocorticosteroid on them. Characterisation of a SAT-1 outbreak of foot-and-mouth disease in captive African buffalo (Syncerus caffer): clinical symptoms, genetic characterisation and phylogenetic comparison of outbreak isolates. Microvilli which project over the uppermost epithelial cells only occasionally contain a filamentous internal structure.

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Due to species specificity of HCMV, animal models are frequently used to study CMV pathogenesis. This type of SLE differs from drug-induced lupus-like syndromes by a high level of anti-double helix DNA antibodies and by the renal lesions observed. Identification of cyclin D1- and estrogen-regulated genes contributing to breast carcinogenesis and progression.

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These results indicate that CMV, HHV-6, and HHV-7 are bystanders rather than cofactors in the oncogenesis of cervical cancer. Enteric nematode infection induces a type 2 immune response with polarization of macrophages toward the alternatively activated phenotype (M2). Their differentiation from B cells entails a profound cellular reshaping inherently associated with stress. Measurement of lead in blood by graphite furnace atomic absorption spectrometry. Mare basalts may contain hydrogen-rich apatite, but lunar magmas were most likely poor in hydrogen, in agreement with the volatile depletion that is both observed in lunar rocks and required for canonical giant-impact models of the formation of the Moon.

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The recent availability of new high-throughput glycoanalytical tools enables a more profound and efficient investigation in large patient cohorts and helps to gain new insights in the complex mechanism of the underlying disease pathways. To evaluate the effect of the non-steroidal anti-inflammtory drug carprofen on the lumbar cerebrospinal fluid (CSF) concentration of noradrenaline (NA) and serotonin (5-HT) in non-stimulated (Part I) and surgically stimulated (Part II) sheep. This association appears to be biologically plausible, and investigations in atherosclerosis animal models demonstrate larger atheroma sizes in animals infected with the periodontal pathogen, Porphyromonas gingivalis, compared with control animals.

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Of 123 cases, 35 cases (36 sides) were reducible and 88 cases (90 sides) were irreducible. A case report of successful treatment with three self-expanding metallic stents. Effects of must concentration techniques on wine isotopic parameters. Cidex, Sporox, Steris 20, ethylene oxide gas, and isopropyl alcohol, in combination with manual cleaning, each achieved a 6-log or greater reduction of the mycobacterial inoculum.

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Results suggest that younger and low-performing preterm children show signs of less neural efficiency in frontal brain areas. This is not restored by the addition of ram seminal plasma which, however, reverses the concurrent head agglutination. GB content in the leaves was higher at the beginning of unfolding stage and decreased during maturation and senescence. Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context.

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The authors describe their laparoscopic repair of perforation using passing sutures and an endoscopic linear stapler. We also identified two nuclear export signals (NES, aa221-236, and 325-364), however, only the nuclear export signal (aa325-364) was found to be functional in the context of the full-length N protein. Polyunsaturated fatty acids in the developing human brain, red cells and plasma: influence of nutrition and peroxisomal disease. Dynamic and static irritation of the bone, zone of reformation, aseptic necroses and osteochondritis dissecans

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This systematic review and meta-analysis showed that DNR orders are positively associated with multimorbidity, and especially with three morbidities, which are cognitive impairment, cancer and stroke. The complexed c-Jun exhibits a decreased electrophoretic mobility corresponding to a more highly phosphorylated state.

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It is proposed to consider the priority critical factors of life quality of adolescents the level of material well-being and psychological climate in the school, physical and social activity, behavioral risk factors. In part, differential recognition by T cells of mHags specifically expressed in hematopoietic cells, including the malignant cells from the recipient may result in GVL reactivity without concurrent GVHD. No difference was noted in the clinical evolution of this arrhythmia and the more commonly observed unifocal AIVR.

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These results suggest that unlike P-gp, BCRP may play a role in leukemia cellular resistance to flavopiridol. Acute spinal cord disorders are challenging, as they present a wide array of differential diagnosis and may lead to devastating sequelae. The epithelial reticular cell layer lining the perivascular spaces was extensively stained with cytokeratin, but the expression of cytokeratin showed an age-dependent decrease. Clinical effect and transfer into the wound exudate of cefroxadine used in the treatment of soft tissue infection

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However, the mechanisms that link cell cycle exit with differentiation remain poorly understood. The complex processing within this nucleus is reminiscent of the feedback loops in the auditory system. Following delivery, transsphenoidal pituitary surgery was performed, confirming the presence of a prolactin-producing adenoma. Most information about pharmacokinetics of antimicrobial agents is obtained from studies in healthy volunteers. Polyelectrolyte conditioning is a common practice in wastewater management.

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MiR-129-5p is down-regulated and involved in the growth, apoptosis and migration of medullary thyroid carcinoma cells through targeting RET. Significant Pharmacokinetic Interactions Between Quinine and Ampicillin-Cloxacillin Combination.

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Bone histomorphometric analysis in familial hypocalciuric hypercalcaemia. Metacognitive development of deaf children: lessons from the appearance-reality and false belief tasks.

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Carbapenem-resistant Pseudomonas aeruginosa-carrying VIM-2 metallo-beta-lactamase determinants, Croatia. Bosentan (100 mg/kg/day) was given to the bosentan-treated group for 7 days and desloratadine (10 mg/kg/day) was administered to the antihistaminic-treated group for 7 days. The tumor produces enamel or enamel matrix, dentin and cementum. Asymmetric reduction and oxidation of aromatic ketones and alcohols using W110A secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus. The study was conducted in a private practice located in a rural town.

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Development of the acrosome and alignment, elongation and entrenchment of spermatids in procarbazine-treated rats. This elevation discrimination task was carried out in-between a verbal WM test, in which a sequence of six digits (to be remembered for report at the end of the trial) was presented either in numerically ascending or random order (i.e., low and high load conditions, respectively). The results of the alpha EGOT did not indicate any significant differences between the postpartum, depressed patients and any of the control groups. Our analyses began with the early phases of healing, and continued until the implants were completely osseointegrated.

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freundii to aminoglycosides and ciprofloxacin decreased markedly during the period from 1987 to 1998. A changing pattern of cerebral palsy and its implications for the early detection of motor disorders in children. A theoretically based crystallographic-phase refinement technique also suggested that there was the equivalent of two fully occupied water molecules within the apolar cavity. Here we present a protocol that preserves GFP and mCherry fluorescence in mammalian cells embedded in resin with electron contrast to reveal cellular ultrastructure. Such variations show how left ventricular tissue increases after the first years of life, and also that times above 5 msec over those found for any age group are indicative of left ventricular hypertrophy.

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Cloning, properties, site-directed mutagenesis analysis of the subunit structure, tissue distribution and regulation of expression of the type-C eel natriuretic peptide receptor. The most common side effect was tenderness of the testis and/or scrotum (5 cases). Arterial pressure measurements correlated to symptoms and signs of peripheral arterial disease. Cloning of cNDAs involved in malignant transformation induced by glycidyl methacrylate

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Links between literacy skills and accurate spatial relations in representations of the face: comparison of preschoolers, school children, dyslexics, and mentally retarded. Jejunum is one of the most frequently used free flaps in esophagus reconstruction. The hollow-shaped species abundance distribution (SAD) and its allied rank abundance distribution (RAD)-showing that abundance is unevenly distributed among species-are some of the most studied patterns in ecology. Further, expression patterns of specific genes provide important information at diagnosis for patients with AML and ALL that may be used for the discrimination from other leukemias.

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Prompts showed, furthermore, to stimulate children of a low SES slightly more to reuse an intervention website, which is often a difficult target group in terms of stimulating participation. The experimental SIADH rat model was developed by means of continuous administration of arginine vasopressin (AVP) via a subcutaneously implanted osmotic mini pump, and hyponatremia was induced by additional water loading. The interaction between IRK and IRKI was confirmed by an in vitro pull-down assay and supported by their simultaneous expression in actively dividing cells in meristems. Long-term (21-25 days) lithium treatment accentuated m-chlorophenylpiperazine (m-CPP, a 5-HT agonist) induced decreases in food intake. Four strains of Actinomyces naeslundii, two strains of Corynebacterium matruchotii and one of two strains of Actinomyces odontolyticus partially or totally removed sialic acid, while two strains of Propionibacterium propionicus and the other strain of A.

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Certain individuals are resistant to HIV-1 infection, despite repeated exposure to the virus. Screening for SCD is being carried out by Government of Chhattisgarh. This study aimed to assess provider attitudes about glucose testing for adults prescribed second-generation antipsychotic medication. However, the cellular and molecular mechanisms that underlie these effects remain poorly understood.

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Coping with occupational stress in an accident and emergency department. She underwent another endoscopy and a biopsy was performed for multiple large and deep specimens. The aim of this study was to evaluate the accuracy of simple radiography, ultrasound and magnetic resonance imaging (MRI) in diagnosing rotator cuff injuries, comparing their findings with open or arthroscopic surgery findings. The research on GG-based formulations has been focused on optimization of the therapy by designing CR dosage forms with a minimum number of excipients. This is the first description of hip osteoarthritis using unenhanced clinical CT in which we describe the co-localisation of posterior osteophytes and joint space narrowing for the first time.

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Consistent with the most recent research, it appears to be both the nature of the illness stimuli and the depression status of the patient that determines cognitive bias in chronically ill populations. This study verifies the significant morbidity associated with an undiagnosed or nonoperatively treated PMTFF. Podotrochlosis--significance and incidence of X-ray-determined changes in the navicular bone Optical coherence tomography was useful in evaluating the site of the hemorrhage in the chorioretinal layers caused by blunt ocular trauma.

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In this commentary, the general mechanisms of GR action will be addressed and a proteomic-based method to study GR-interacting proteins will be described in brief. Occupational identity is an emerging concept in the occupational therapy literature. There was no overall trend toward increasing use of imaging in inpatients once an adjustment for severity of illness was made. Presentation with gastrointestinal symptoms and high case fatality associated with group W meningococcal disease (MenW) in teenagers, England, July 2015 to January 2016.

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These results suggest that lepidimoic acid may affect glycolytic metabolism in the Amaranthus seedlings by increasing the activity of PFP due to increasing level of Fru-2,6-P2. Survey of Provider Transfusion Practices for Oncology Patients in an Academic Medical Center. No changes in the use of antidepressants were allowed 6 weeks before and during the intervention.

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Results of catamnestic studies on course and consequences of cranium and brain injuries in 1648 cases Conversion of external fixation to open reduction and internal fixation for complex distal radius fractures.

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The variability of ventricular arrhythmias (VA) among different days of the week is not well detected by one-day Holter monitoring. Ten inpatients with anorexia nervosa and bulimia nervosa abusing alcohol for 1-4 years have been examined. This study was done as a Doctoral dissertation at New York University, School of Education, Division of Nursing. We compared the premorbid social adjustment of 38 schizophrenic patients with that of 20 manic patients.

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Atrial dilatation is an important risk factor for atrial fibrillation (AF). Although increased fluidity might be involved in the increased kD for non-saturable uptake, the concentration-specific stimulating effect of polyarginine suggests a gating mechanism.

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The effects of visual barriers on exiting behavior in a dementia care unit. mRNA fluorescence in situ hybridization (FISH) for RIP2 was performed on 17 stage III breast cancers to determine if there was a correlation between RIP2 expression and lymph node involvement.

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There were 127 diagnoses of malignancy confirmed in 5,011 patients, 62 in the reproductive system and 62 in other organ systems. Carcinoembryonic antigen and albumin predict survival in patients with advanced colon and rectal cancer.

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We hypothesized that intrinsic genetic factors influence the severity of joint contractures developing secondary to joint immobilization. This species of the Compositae family, native to the Caribbean region, has spread widely in India, causing allergic contact dermatitis from its content of sesquiterpene lactones, and has recently appeared in Australia. Renal putrescine rose sharply and the amounts of spermidine were also increased. cDNA sequences of malate dehydrogenase (MDH) were cloned from various species, and MDH was identified to play an important role in cell energy metabolism. In cervical cancer, nm23-H1 is probably involved in cervical carcinogenesis and correlated with some aggressive parameters.

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Measuring patient safety in ambulatory care: potential for identifying medical group drug-drug interaction rates using claims data. Alteration of gene expression of G protein-coupled receptors in endocrine disruptors-caused hyperactive rats. Patients with acute ischemic stroke admitted between January 2005 and June 2006 who were treated with intravenous rt-PA or endovascular-based reperfusion were reviewed. Concentration and heterogeneity of CEA-like substance in gastric juice were studied using radioimmunoassay.

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Cystinotic cells pre-treated with cysteamine, normalizing cystine content, display a four- to fivefold decrease in apoptosis, while normal cells pre-treated with cystine dimethylester, increasing lysosomal cystine, exhibit a fivefold increase in apoptosis. We now report that striatal target cells influence the morphology of dopaminergic neurons as well. Both ethanol and water extracts of corni fructus produced higher DPPH radical scavenging activity than hexane, chloroform, and ethyl acetate extracts. The results show that an adjustment is principally advisable and is generally associated with a reduction of the differences in treatment results. Specific language impairment (SLI) was defined as language impairment concurrent with a cognitive score not more than one SD below the normative mean.

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Most of those choosing family practice did not change their career choice between entry to and exit from the school. Blood circulation of the flaps was abundant except one with distal edge necrosis. These peroxisomal functions are maintained by import of newly synthesized proteins containing one of two peroxisomal targeting signals known as PTS1 and PTS2. Restriction enzymes Asp718 and BstEII were used to analyze the genes at nucleotide 258, tetralab pure gold review and BssHII and Kas I were used to analyze the genes at nucleotide 523. Some of these stellate cell types constitute major projection neurones into the brainstem and directly into the inferior colliculus, while others are implicated in more local processing.

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Pre-operative paradigms include the optimal plaque control and smoking counselling. In phylogenetic analysis, the results supported the morphological hypothesis. In order to meet the assumptions necessary for application of linear statistics to clinical measurement studies, Rasch analysis was used to transform ordinal scales into linear measures. The sensitivity of the resulting standard curve was such as to permit quantitation of pg amounts of the reduced metabolites. The ibufen suspension vaikams multikai anterior and posterior cingulate gyri were hypometabolic only in the pre-treatment group.

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However, granulocyte colony-stimulating factor exerts potent pro- and anti-inflammatory effects that could influence secondary injury, and outcome, after traumatic brain injury. This study enrolled patients with stage Ib2-IIb cervical cancer who underwent surgery with (NACT group) or without (control group) prior cisplatin-based chemotherapy. Evidence supporting the assignment of the two tensor components to extracellular and intracellular water fractions is provided by an NMR spectroscopic esoz 20 mg granulado na investigation of homogeneous samples of brain tissue.

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Smoking behavior and participation in screening for lung, gastric, and colorectal cancers Normal values for interpupillary, inner canthal and outer tauxib 90 mg etoricoxib arcoxia canthal distances in an Indian population. Each seta branches into hundreds of 200-nm spatulae that make intimate contact with a variety of surface profiles. Compressive strength, dimensional change during hardening and residual mercury content of three high-copper spherical particle amalgams (Tytin, Logic and Valiant), two admix amalgams (Dispersalloy and Permite C) and a conventional lathe-cut amalgam (New True Dentalloy) were determined as a function of condensation pressure and trituration time. Thus, mitochondria from TNFalpha-TG failing hearts demonstrate structural and functional abnormalities, with reduced tolerance to stress manifested by impaired bioenergetics and increased susceptibility to injury.

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Objective and subjective nCPAP use, tagremin 400 mg coq10 upper airway symptoms, and treatment satisfaction were compared. Home Cooking and Phenolics: Effect of Thermal Treatment and Addition of Extra Virgin Olive Oil on the Phenolic Profile of Tomato Sauces.

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Resident reflections on end-of-life education: a mixed-methods study of the 3 Wishes Project. By using a Sepharose-immobilized lectin, concanavalin A, we isolated a fraction enriched with LRV polyprotein-specific protease activity. Effects of extracellular visfatin on cultured breast cancer cells were subsyde-cr capsules side effects examined, followed by in vivo investigation of tumor growth and metastasis in xenograft animal models. Tramadol is a therapeutic option for the control of neuropathic pain in patients with cancer, and appears to improve quality of life in these patients.

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Early left-right asymmetries during axial morphogenesis in the chick embryo. However, the expression and localization of orexin receptors is not elicited well. These findings are compatible with the hypothesis that thuoc tatanol caps frictional stress due to airflow through an obstructed nostril induces trauma and swelling of the nasal mucosa of patients with allergic rhinitis.

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Recurrent UTI is typically defined as three or more UTIs within 12 months, or two or more occurrences within six months. Developing the FARSEEING Taxonomy of Technologies: Classification and description of technology use (including ICT) in falls prevention studies. The difference in total- and negative side effects of augmentin and alcohol LDL-cholesterol lowering between the 2 soy-protein supplements suggests an effect attributable to the isoflavone-containing fraction. Takotsubo cardiomyopathy which is characterised by a transient left ventricular wall motion abnormality was first described in 1990.

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